Prevalence of hepatitis B and C viruses among migrant workers in Qatar

Gheyath K Nasrallah; Hiam Chemaitelly; Ahmed I A Ismail; Parveen B Nizamuddin; Duaa W Al-Sadeq; Farah M Shurrab; Fathima H Amanullah; Tasneem H Al-Hamad; Khadija N Mohammad; Maryam A Alabdulmalek; Reham A Al Kahlout; Ibrahim Al-Shaar; Manal A Elshaikh; Mazen N Abouassali; Ibrahim W Karimeh; Mutaz M Ali; Houssein H Ayoub; Sami Abdeen; Ashraf Abdelkarim; Faisal Daraan; Ahmed Ibrahim Hashim Elhaj Ismail; Nahid Mostafa; Mohamed Sahl; Jinan Suliman; Elias Tayar; Hasan Ali Kasem; Meynard J A Agsalog; Bassam K Akkarathodiyil; Ayat A Alkhalaf; Mohamed Morhaf M H Alakshar; Abdulsalam Ali A H Al-Qahtani; Monther H A Al-Shedifat; Anas Ansari; Ahmad Ali Ataalla; Sandeep Chougule; Abhilash K K V Gopinathan; Feroz J Poolakundan; Sanjay U Ranbhise; Saed M A Saefan; Mohamed M Thaivalappil; Abubacker S Thoyalil; Inayath M Umar; Einas Al Kuwari; Peter Coyle; Andrew Jeremijenko; Anvar Hassan Kaleeckal; Hanan F Abdul Rahim; Hadi M Yassine; Asmaa A Al Thani; Odette Chaghoury; Mohamed Ghaith Al Kuwari; Elmoubasher Farag; Roberto Bertollini; Hamad Eid Al Romaihi; Abdullatif Al Khal; Mohamed H Al-Thani; Laith J Abu-Raddad

doi:10.1038/s41598-024-61725-9

Prevalence of hepatitis B and C viruses among migrant workers in Qatar

Gheyath K Nasrallah
, Hiam Chemaitelly
, Ahmed I A Ismail
, Parveen B Nizamuddin
, Duaa W Al-Sadeq
, Farah M Shurrab
, Fathima H Amanullah
, Tasneem H Al-Hamad
, Khadija N Mohammad
, Maryam A Alabdulmalek
, Reham A Al Kahlout
, Ibrahim Al-Shaar
, Manal A Elshaikh
, Mazen N Abouassali
, Ibrahim W Karimeh
, Mutaz M Ali
, Houssein H Ayoub
, Sami Abdeen
, Ashraf Abdelkarim
, Faisal Daraan

Ahmed Ibrahim Hashim Elhaj Ismail, Nahid Mostafa, Mohamed Sahl, Jinan Suliman, Elias Tayar, Hasan Ali Kasem, Meynard J A Agsalog, Bassam K Akkarathodiyil, Ayat A Alkhalaf, Mohamed Morhaf M H Alakshar, Abdulsalam Ali A H Al-Qahtani, Monther H A Al-Shedifat, Anas Ansari, Ahmad Ali Ataalla, Sandeep Chougule, Abhilash K K V Gopinathan, Feroz J Poolakundan, Sanjay U Ranbhise, Saed M A Saefan, Mohamed M Thaivalappil, Abubacker S Thoyalil, Inayath M Umar, Einas Al Kuwari, Peter Coyle, Andrew Jeremijenko, Anvar Hassan Kaleeckal, Hanan F Abdul Rahim, Hadi M Yassine, Asmaa A Al Thani, Odette Chaghoury, Mohamed Ghaith Al Kuwari, Elmoubasher Farag, Roberto Bertollini, Hamad Eid Al Romaihi, Abdullatif Al Khal, Mohamed H Al-Thani, Laith J Abu-Raddad

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

106 Downloads (Pure)

Abstract

Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft and manual workers (CMWs), constituting 60% of the country's population. Sera collected during a nationwide COVID-19 population-based cross-sectional survey on CMWs between July 26 and September 9, 2020, underwent testing for HBsAg and HCV antibodies. Reactive samples underwent confirmatory testing, and logistic regression analyses were employed to explore associations with HBV and HCV infections. Among 2528 specimens tested for HBV infection, 15 were reactive, with 8 subsequently confirmed positive. Three samples lacked sufficient sera for confirmatory testing but were included in the analysis through multiple imputations. Prevalence of current HBV infection was 0.4% (95% CI 0.2-0.7%). Educational attainment and occupation were significantly associated with current HBV infection. For HCV infection, out of 2607 specimens tested, 46 were reactive, and 23 were subsequently confirmed positive. Prevalence of lifetime HCV infection was 0.8% (95% CI 0.5-1.2%). Egyptians exhibited the highest prevalence at 6.5% (95% CI 3.1-13.1%), followed by Pakistanis at 3.1% (95% CI 1.1-8.0%). Nationality, geographic location, and occupation were significantly associated with lifetime HCV infection. HBV infection is relatively low among CMWs, while HCV infection falls within the intermediate range, both compared to global and regional levels.

Original language	English
Article number	11275
Number of pages	11
Journal	Scientific Reports
Volume	14
Early online date	17 May 2024
DOIs	https://doi.org/10.1038/s41598-024-61725-9
Publication status	Early online date - 17 May 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Qatar - epidemiology
Transients and Migrants - statistics & numerical data
Qatar
Humans
Female
HBV
Adult
Male
Prevalence
Young Adult
Hepatitis B virus - isolation & purification - immunology
Hepatitis
Workers
Hepatitis B - epidemiology - virology - blood
Infection
Adolescent
Hepatitis B Surface Antigens - blood
HCV
COVID-19 - epidemiology - virology
Hepatitis C Antibodies - blood
Cross-Sectional Studies
Hepatitis C - epidemiology
Middle Aged
Cross-sectional
Hepacivirus - immunology - isolation & purification

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10.1038/s41598-024-61725-9Licence: CC BY

Prevalence of hepatitis B and C viruses among migrant workers in Qatar
© 2024 The Authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 998 KBLicence: CC BY

Cite this

Nasrallah, G. K., Chemaitelly, H., Ismail, A. I. A., Nizamuddin, P. B., Al-Sadeq, D. W., Shurrab, F. M., Amanullah, F. H., Al-Hamad, T. H., Mohammad, K. N., Alabdulmalek, M. A., Al Kahlout, R. A., Al-Shaar, I., Elshaikh, M. A., Abouassali, M. N., Karimeh, I. W., Ali, M. M., Ayoub, H. H., Abdeen, S., Abdelkarim, A., ... Abu-Raddad, L. J. (2024). Prevalence of hepatitis B and C viruses among migrant workers in Qatar. Scientific Reports, 14, Article 11275. Advance online publication. https://doi.org/10.1038/s41598-024-61725-9

@article{c7781b793a5642ee8e1771145fb8dfd5,

title = "Prevalence of hepatitis B and C viruses among migrant workers in Qatar",

abstract = "Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft and manual workers (CMWs), constituting 60\% of the country's population. Sera collected during a nationwide COVID-19 population-based cross-sectional survey on CMWs between July 26 and September 9, 2020, underwent testing for HBsAg and HCV antibodies. Reactive samples underwent confirmatory testing, and logistic regression analyses were employed to explore associations with HBV and HCV infections. Among 2528 specimens tested for HBV infection, 15 were reactive, with 8 subsequently confirmed positive. Three samples lacked sufficient sera for confirmatory testing but were included in the analysis through multiple imputations. Prevalence of current HBV infection was 0.4\% (95\% CI 0.2-0.7\%). Educational attainment and occupation were significantly associated with current HBV infection. For HCV infection, out of 2607 specimens tested, 46 were reactive, and 23 were subsequently confirmed positive. Prevalence of lifetime HCV infection was 0.8\% (95\% CI 0.5-1.2\%). Egyptians exhibited the highest prevalence at 6.5\% (95\% CI 3.1-13.1\%), followed by Pakistanis at 3.1\% (95\% CI 1.1-8.0\%). Nationality, geographic location, and occupation were significantly associated with lifetime HCV infection. HBV infection is relatively low among CMWs, while HCV infection falls within the intermediate range, both compared to global and regional levels.",

keywords = "Qatar - epidemiology, Transients and Migrants - statistics \& numerical data, Qatar, Humans, Female, HBV, Adult, Male, Prevalence, Young Adult, Hepatitis B virus - isolation \& purification - immunology, Hepatitis, Workers, Hepatitis B - epidemiology - virology - blood, Infection, Adolescent, Hepatitis B Surface Antigens - blood, HCV, COVID-19 - epidemiology - virology, Hepatitis C Antibodies - blood, Cross-Sectional Studies, Hepatitis C - epidemiology, Middle Aged, Cross-sectional, Hepacivirus - immunology - isolation \& purification",

author = "Nasrallah, \{Gheyath K\} and Hiam Chemaitelly and Ismail, \{Ahmed I A\} and Nizamuddin, \{Parveen B\} and Al-Sadeq, \{Duaa W\} and Shurrab, \{Farah M\} and Amanullah, \{Fathima H\} and Al-Hamad, \{Tasneem H\} and Mohammad, \{Khadija N\} and Alabdulmalek, \{Maryam A\} and \{Al Kahlout\}, \{Reham A\} and Ibrahim Al-Shaar and Elshaikh, \{Manal A\} and Abouassali, \{Mazen N\} and Karimeh, \{Ibrahim W\} and Ali, \{Mutaz M\} and Ayoub, \{Houssein H\} and Sami Abdeen and Ashraf Abdelkarim and Faisal Daraan and Ismail, \{Ahmed Ibrahim Hashim Elhaj\} and Nahid Mostafa and Mohamed Sahl and Jinan Suliman and Elias Tayar and Kasem, \{Hasan Ali\} and Agsalog, \{Meynard J A\} and Akkarathodiyil, \{Bassam K\} and Alkhalaf, \{Ayat A\} and Alakshar, \{Mohamed Morhaf M H\} and Al-Qahtani, \{Abdulsalam Ali A H\} and Al-Shedifat, \{Monther H A\} and Anas Ansari and Ataalla, \{Ahmad Ali\} and Sandeep Chougule and Gopinathan, \{Abhilash K K V\} and Poolakundan, \{Feroz J\} and Ranbhise, \{Sanjay U\} and Saefan, \{Saed M A\} and Thaivalappil, \{Mohamed M\} and Thoyalil, \{Abubacker S\} and Umar, \{Inayath M\} and \{Al Kuwari\}, Einas and Peter Coyle and Andrew Jeremijenko and Kaleeckal, \{Anvar Hassan\} and \{Abdul Rahim\}, \{Hanan F\} and Yassine, \{Hadi M\} and \{Al Thani\}, \{Asmaa A\} and Odette Chaghoury and \{Al Kuwari\}, \{Mohamed Ghaith\} and Elmoubasher Farag and Roberto Bertollini and \{Al Romaihi\}, \{Hamad Eid\} and \{Al Khal\}, Abdullatif and Al-Thani, \{Mohamed H\} and Abu-Raddad, \{Laith J\}",

year = "2024",

month = may,

day = "17",

doi = "10.1038/s41598-024-61725-9",

language = "English",

volume = "14",

journal = "Scientific Reports",

issn = "2045-2322",

publisher = "Nature Research",

}

Nasrallah, GK, Chemaitelly, H, Ismail, AIA, Nizamuddin, PB, Al-Sadeq, DW, Shurrab, FM, Amanullah, FH, Al-Hamad, TH, Mohammad, KN, Alabdulmalek, MA, Al Kahlout, RA, Al-Shaar, I, Elshaikh, MA, Abouassali, MN, Karimeh, IW, Ali, MM, Ayoub, HH, Abdeen, S, Abdelkarim, A, Daraan, F, Ismail, AIHE, Mostafa, N, Sahl, M, Suliman, J, Tayar, E, Kasem, HA, Agsalog, MJA, Akkarathodiyil, BK, Alkhalaf, AA, Alakshar, MMMH, Al-Qahtani, AAAH, Al-Shedifat, MHA, Ansari, A, Ataalla, AA, Chougule, S, Gopinathan, AKKV, Poolakundan, FJ, Ranbhise, SU, Saefan, SMA, Thaivalappil, MM, Thoyalil, AS, Umar, IM, Al Kuwari, E, Coyle, P, Jeremijenko, A, Kaleeckal, AH, Abdul Rahim, HF, Yassine, HM, Al Thani, AA, Chaghoury, O, Al Kuwari, MG, Farag, E, Bertollini, R, Al Romaihi, HE, Al Khal, A, Al-Thani, MH & Abu-Raddad, LJ 2024, 'Prevalence of hepatitis B and C viruses among migrant workers in Qatar', Scientific Reports, vol. 14, 11275. https://doi.org/10.1038/s41598-024-61725-9

TY - JOUR

T1 - Prevalence of hepatitis B and C viruses among migrant workers in Qatar

AU - Nasrallah, Gheyath K

AU - Chemaitelly, Hiam

AU - Ismail, Ahmed I A

AU - Nizamuddin, Parveen B

AU - Al-Sadeq, Duaa W

AU - Shurrab, Farah M

AU - Amanullah, Fathima H

AU - Al-Hamad, Tasneem H

AU - Mohammad, Khadija N

AU - Alabdulmalek, Maryam A

AU - Al Kahlout, Reham A

AU - Al-Shaar, Ibrahim

AU - Elshaikh, Manal A

AU - Abouassali, Mazen N

AU - Karimeh, Ibrahim W

AU - Ali, Mutaz M

AU - Ayoub, Houssein H

AU - Abdeen, Sami

AU - Abdelkarim, Ashraf

AU - Daraan, Faisal

AU - Ismail, Ahmed Ibrahim Hashim Elhaj

AU - Mostafa, Nahid

AU - Sahl, Mohamed

AU - Suliman, Jinan

AU - Tayar, Elias

AU - Kasem, Hasan Ali

AU - Agsalog, Meynard J A

AU - Akkarathodiyil, Bassam K

AU - Alkhalaf, Ayat A

AU - Alakshar, Mohamed Morhaf M H

AU - Al-Qahtani, Abdulsalam Ali A H

AU - Al-Shedifat, Monther H A

AU - Ansari, Anas

AU - Ataalla, Ahmad Ali

AU - Chougule, Sandeep

AU - Gopinathan, Abhilash K K V

AU - Poolakundan, Feroz J

AU - Ranbhise, Sanjay U

AU - Saefan, Saed M A

AU - Thaivalappil, Mohamed M

AU - Thoyalil, Abubacker S

AU - Umar, Inayath M

AU - Al Kuwari, Einas

AU - Coyle, Peter

AU - Jeremijenko, Andrew

AU - Kaleeckal, Anvar Hassan

AU - Abdul Rahim, Hanan F

AU - Yassine, Hadi M

AU - Al Thani, Asmaa A

AU - Chaghoury, Odette

AU - Al Kuwari, Mohamed Ghaith

AU - Farag, Elmoubasher

AU - Bertollini, Roberto

AU - Al Romaihi, Hamad Eid

AU - Al Khal, Abdullatif

AU - Al-Thani, Mohamed H

AU - Abu-Raddad, Laith J

PY - 2024/5/17

Y1 - 2024/5/17

N2 - Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft and manual workers (CMWs), constituting 60% of the country's population. Sera collected during a nationwide COVID-19 population-based cross-sectional survey on CMWs between July 26 and September 9, 2020, underwent testing for HBsAg and HCV antibodies. Reactive samples underwent confirmatory testing, and logistic regression analyses were employed to explore associations with HBV and HCV infections. Among 2528 specimens tested for HBV infection, 15 were reactive, with 8 subsequently confirmed positive. Three samples lacked sufficient sera for confirmatory testing but were included in the analysis through multiple imputations. Prevalence of current HBV infection was 0.4% (95% CI 0.2-0.7%). Educational attainment and occupation were significantly associated with current HBV infection. For HCV infection, out of 2607 specimens tested, 46 were reactive, and 23 were subsequently confirmed positive. Prevalence of lifetime HCV infection was 0.8% (95% CI 0.5-1.2%). Egyptians exhibited the highest prevalence at 6.5% (95% CI 3.1-13.1%), followed by Pakistanis at 3.1% (95% CI 1.1-8.0%). Nationality, geographic location, and occupation were significantly associated with lifetime HCV infection. HBV infection is relatively low among CMWs, while HCV infection falls within the intermediate range, both compared to global and regional levels.

AB - Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft and manual workers (CMWs), constituting 60% of the country's population. Sera collected during a nationwide COVID-19 population-based cross-sectional survey on CMWs between July 26 and September 9, 2020, underwent testing for HBsAg and HCV antibodies. Reactive samples underwent confirmatory testing, and logistic regression analyses were employed to explore associations with HBV and HCV infections. Among 2528 specimens tested for HBV infection, 15 were reactive, with 8 subsequently confirmed positive. Three samples lacked sufficient sera for confirmatory testing but were included in the analysis through multiple imputations. Prevalence of current HBV infection was 0.4% (95% CI 0.2-0.7%). Educational attainment and occupation were significantly associated with current HBV infection. For HCV infection, out of 2607 specimens tested, 46 were reactive, and 23 were subsequently confirmed positive. Prevalence of lifetime HCV infection was 0.8% (95% CI 0.5-1.2%). Egyptians exhibited the highest prevalence at 6.5% (95% CI 3.1-13.1%), followed by Pakistanis at 3.1% (95% CI 1.1-8.0%). Nationality, geographic location, and occupation were significantly associated with lifetime HCV infection. HBV infection is relatively low among CMWs, while HCV infection falls within the intermediate range, both compared to global and regional levels.

KW - Qatar - epidemiology

KW - Transients and Migrants - statistics & numerical data

KW - Qatar

KW - Humans

KW - Female

KW - HBV

KW - Adult

KW - Male

KW - Prevalence

KW - Young Adult

KW - Hepatitis B virus - isolation & purification - immunology

KW - Hepatitis

KW - Workers

KW - Hepatitis B - epidemiology - virology - blood

KW - Infection

KW - Adolescent

KW - Hepatitis B Surface Antigens - blood

KW - HCV

KW - COVID-19 - epidemiology - virology

KW - Hepatitis C Antibodies - blood

KW - Cross-Sectional Studies

KW - Hepatitis C - epidemiology

KW - Middle Aged

KW - Cross-sectional

KW - Hepacivirus - immunology - isolation & purification

U2 - 10.1038/s41598-024-61725-9

DO - 10.1038/s41598-024-61725-9

M3 - Article

C2 - 38760415

SN - 2045-2322

VL - 14

JO - Scientific Reports

JF - Scientific Reports

M1 - 11275

ER -

Prevalence of hepatitis B and C viruses among migrant workers in Qatar

Abstract

UN SDGs

Keywords

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