Prevalence of polypoidal choroidal vasculopathy using non-ICGA based criteria

Beau J Fenner, Kelvin Y C Teo, Yih Chung Tham, Usha Chakravarthy, Chui Ming Gemmy Cheung

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Polypoidal choroidal vasculopathy (PCV) is a form of neovascular AMD characterized by polypoidal lesions and branching vascular networks. Diagnosis has traditionally required the use of invasive indocyanine green angiography, though recently a validated non-invasive diagnostic system has been developed that identified PCV-specific features using optical coherence tomography (OCT) and color fundus photography. In this work we applied this new system to a large population-based cohort of ethnic Chinese and successfully identified PCV and related anatomical features. We estimated a population prevalence of 0.31% (95% CI, 0.06-0.91%) and additionally demonstrate that PCV-related retinal findings were relatively rare in the population.
Original languageEnglish
Pages (from-to) 179-181
JournalOpthalmology Retina
Issue number2
Early online date24 Sept 2021
Publication statusPublished - 02 Feb 2022


  • Age-related macular degeneration (AMD)
  • neovascular AMD (nAMD)
  • optical coherence tomography
  • double layer sign (DLS)
  • pigment epithelial detachment (PED) polypoidal choroidal vasculopathy (PCV)


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