Principles for the post-GWAS functional characterization of cancer risk loci

Matthew L Freedman; Alvaro N A Monteiro; Simon A Gayther; Gerhard A Coetzee; Angela Risch; Christoph Plass; Graham Casey; Mariella De Biasi; Chris Carlson; David Duggan; Michael James; Pengyuan Liu; Jay W Tichelaar; Haris G Vikis; Ming You; Ian G Mills

doi:10.1038/ng.840

Principles for the post-GWAS functional characterization of cancer risk loci

Matthew L Freedman, Alvaro N A Monteiro, Simon A Gayther, Gerhard A Coetzee, Angela Risch, Christoph Plass, Graham Casey, Mariella De Biasi, Chris Carlson, David Duggan, Michael James, Pengyuan Liu, Jay W Tichelaar, Haris G Vikis, Ming You, Ian G Mills

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

359 Citations (Scopus)

Original language	English
Pages (from-to)	513-8
Number of pages	6
Journal	Nature Genetics
Volume	43
Issue number	6
DOIs	https://doi.org/10.1038/ng.840
Publication status	Published - Jun 2011

Keywords

Catechols
Gene Expression
Genetic Predisposition to Disease
Genetic Variation
Genome-Wide Association Study
Inositol
Models, Biological
Polymorphism, Single Nucleotide
Quantitative Trait Loci
Regulatory Sequences, Nucleic Acid
Risk

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/ng.840

Cite this

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title = "Principles for the post-GWAS functional characterization of cancer risk loci",

keywords = "Catechols, Gene Expression, Genetic Predisposition to Disease, Genetic Variation, Genome-Wide Association Study, Inositol, Models, Biological, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Regulatory Sequences, Nucleic Acid, Risk",

author = "Freedman, {Matthew L} and Monteiro, {Alvaro N A} and Gayther, {Simon A} and Coetzee, {Gerhard A} and Angela Risch and Christoph Plass and Graham Casey and {De Biasi}, Mariella and Chris Carlson and David Duggan and Michael James and Pengyuan Liu and Tichelaar, {Jay W} and Vikis, {Haris G} and Ming You and Mills, {Ian G}",

year = "2011",

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doi = "10.1038/ng.840",

language = "English",

volume = "43",

pages = "513--8",

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T1 - Principles for the post-GWAS functional characterization of cancer risk loci

AU - Freedman, Matthew L

AU - Monteiro, Alvaro N A

AU - Gayther, Simon A

AU - Coetzee, Gerhard A

AU - Risch, Angela

AU - Plass, Christoph

AU - Casey, Graham

AU - De Biasi, Mariella

AU - Carlson, Chris

AU - Duggan, David

AU - James, Michael

AU - Liu, Pengyuan

AU - Tichelaar, Jay W

AU - Vikis, Haris G

AU - You, Ming

AU - Mills, Ian G

PY - 2011/6

Y1 - 2011/6

KW - Catechols

KW - Gene Expression

KW - Genetic Predisposition to Disease

KW - Genetic Variation

KW - Genome-Wide Association Study

KW - Inositol

KW - Models, Biological

KW - Polymorphism, Single Nucleotide

KW - Quantitative Trait Loci

KW - Regulatory Sequences, Nucleic Acid

KW - Risk

U2 - 10.1038/ng.840

DO - 10.1038/ng.840

M3 - Article

C2 - 21614091

SN - 1061-4036

VL - 43

SP - 513

EP - 518

JO - Nature Genetics

JF - Nature Genetics

IS - 6

ER -