Prognostic Impact of Monocyte Count at Presentation in Mantle Cell Lymphoma

K. Aprile von Hohenstaufen; A. Conconi; C. P. de Campos; S. Franceschetti; F. Bertoni; G. Margiotta Casaluci; A. Stathis; M. Ghielmini; G. Stussi; F. Cavalli; G. Gaidano; E. Zucca

doi:10.1111/bjh.12409

Prognostic Impact of Monocyte Count at Presentation in Mantle Cell Lymphoma

K. Aprile von Hohenstaufen, A. Conconi, C. P. de Campos, S. Franceschetti, F. Bertoni, G. Margiotta Casaluci, A. Stathis, M. Ghielmini, G. Stussi, F. Cavalli, G. Gaidano, E. Zucca

School of Electronics, Electrical Engineering and Computer Science

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Abstract

Increased number of circulating monocytes at presentation has been recently associated with shorter survival in Hodgkin lymphoma, follicular lymphoma and diffuse large B cell lymphoma. This study aimed to assess the prognostic impact of the absolute monocyte count (AMC) at diagnosis in mantle cell lymphoma (MCL). From the series of MCL cases recorded on the databases of the Oncology Institute of Southern Switzerland in Bellinzona (Switzerland) and the Division of Haematology of the Amedeo Avogadro University of Eastern Piedmont in Novara (Italy), the AMC at diagnosis was available in 97 cases. Cox regression was used for both univariate and multivariate analysis. With a median follow up of 7 years, the 5-year overall survival (OS) was 29% for patients with AMC >500/ul and 62% for patients with AMC

Original language	English
Pages (from-to)	465-473
Number of pages	9
Journal	British Journal of Haematology
Volume	162(4)
DOIs	https://doi.org/10.1111/bjh.12409
Publication status	Published - 2013

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title = "Prognostic Impact of Monocyte Count at Presentation in Mantle Cell Lymphoma",

abstract = "Increased number of circulating monocytes at presentation has been recently associated with shorter survival in Hodgkin lymphoma, follicular lymphoma and diffuse large B cell lymphoma. This study aimed to assess the prognostic impact of the absolute monocyte count (AMC) at diagnosis in mantle cell lymphoma (MCL). From the series of MCL cases recorded on the databases of the Oncology Institute of Southern Switzerland in Bellinzona (Switzerland) and the Division of Haematology of the Amedeo Avogadro University of Eastern Piedmont in Novara (Italy), the AMC at diagnosis was available in 97 cases. Cox regression was used for both univariate and multivariate analysis. With a median follow up of 7 years, the 5-year overall survival (OS) was 29% for patients with AMC >500/ul and 62% for patients with AMC ",

author = "{von Hohenstaufen}, {K. Aprile} and A. Conconi and {de Campos}, {C. P.} and S. Franceschetti and F. Bertoni and {Margiotta Casaluci}, G. and A. Stathis and M. Ghielmini and G. Stussi and F. Cavalli and G. Gaidano and E. Zucca",

year = "2013",

doi = "10.1111/bjh.12409",

language = "English",

volume = "162(4)",

pages = "465--473",

journal = "British Journal of Haematology",

issn = "0007-1048",

publisher = "John Wiley & Sons Inc.",

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TY - JOUR

T1 - Prognostic Impact of Monocyte Count at Presentation in Mantle Cell Lymphoma

AU - von Hohenstaufen, K. Aprile

AU - Conconi, A.

AU - de Campos, C. P.

AU - Franceschetti, S.

AU - Bertoni, F.

AU - Margiotta Casaluci, G.

AU - Stathis, A.

AU - Ghielmini, M.

AU - Stussi, G.

AU - Cavalli, F.

AU - Gaidano, G.

AU - Zucca, E.

PY - 2013

Y1 - 2013

N2 - Increased number of circulating monocytes at presentation has been recently associated with shorter survival in Hodgkin lymphoma, follicular lymphoma and diffuse large B cell lymphoma. This study aimed to assess the prognostic impact of the absolute monocyte count (AMC) at diagnosis in mantle cell lymphoma (MCL). From the series of MCL cases recorded on the databases of the Oncology Institute of Southern Switzerland in Bellinzona (Switzerland) and the Division of Haematology of the Amedeo Avogadro University of Eastern Piedmont in Novara (Italy), the AMC at diagnosis was available in 97 cases. Cox regression was used for both univariate and multivariate analysis. With a median follow up of 7 years, the 5-year overall survival (OS) was 29% for patients with AMC >500/ul and 62% for patients with AMC

AB - Increased number of circulating monocytes at presentation has been recently associated with shorter survival in Hodgkin lymphoma, follicular lymphoma and diffuse large B cell lymphoma. This study aimed to assess the prognostic impact of the absolute monocyte count (AMC) at diagnosis in mantle cell lymphoma (MCL). From the series of MCL cases recorded on the databases of the Oncology Institute of Southern Switzerland in Bellinzona (Switzerland) and the Division of Haematology of the Amedeo Avogadro University of Eastern Piedmont in Novara (Italy), the AMC at diagnosis was available in 97 cases. Cox regression was used for both univariate and multivariate analysis. With a median follow up of 7 years, the 5-year overall survival (OS) was 29% for patients with AMC >500/ul and 62% for patients with AMC

U2 - 10.1111/bjh.12409

DO - 10.1111/bjh.12409

M3 - Article

SN - 0007-1048

VL - 162(4)

SP - 465

EP - 473

JO - British Journal of Haematology

JF - British Journal of Haematology

ER -

Prognostic Impact of Monocyte Count at Presentation in Mantle Cell Lymphoma

Abstract

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