Prospective investigation of body mass index, colorectal adenoma, and colorectal cancer in the prostate, lung, colorectal, and ovarian cancer screening trial

Cari M Kitahara, Sonja I Berndt, Amy Berrington de González, Helen G Coleman, Robert E Schoen, Richard B Hayes, Wen-Yi Huang

Research output: Contribution to journalArticlepeer-review

54 Citations (Scopus)

Abstract

Obesity has consistently been linked to an increased risk of colorectal cancer, particularly among men. Whether body mass index (BMI) differentially influences the risk across the stages of colorectal cancer development remains unclear. We evaluated the associations of BMI with colorectal adenoma incidence, adenoma recurrence, and cancer in the context of a large screening trial, in which cases and controls had an equal chance for disease detection.
Original languageEnglish
Pages (from-to)2450-2459
JournalJournal of Clinical Oncology
Volume31
Issue number19
DOIs
Publication statusPublished - 01 Jul 2013

Keywords

  • Adenoma
  • Aged
  • Body Mass Index
  • Colorectal Neoplasms
  • Early Detection of Cancer
  • Female
  • Humans
  • Incidence
  • Lung Neoplasms
  • Male
  • Mass Screening
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Obesity
  • Odds Ratio
  • Ovarian Neoplasms
  • Prospective Studies
  • Prostatic Neoplasms
  • Sigmoidoscopy
  • United States

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