Proteomic profiling of the retinal dysplasia and degeneration chick retina

Sorcha Finnegan, Nuala Robson, P.M. Hocking, Aziza Suliman Ali, C.F. Inglehearn, Alan Stitt, Jim Curry

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Purpose: In our previous paper we undertook proteomic analysis of the normal developing chick retina to identify proteins that were differentially expressed during retinal development. In the present paper we use the same proteomic approach to analyze the development and onset of degeneration in the retinal dysplasia and degeneration (rdd) chick. The pathology displayed by the rdd chick resembles that observed in some of the more severe forms of human retinitis pigmentosa.
Original languageEnglish
Pages (from-to)7-17
Number of pages11
JournalMolecular Vision
Volume16
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Ophthalmology

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