Proteomic profiling of the retinal dysplasia and degeneration chick retina

Sorcha Finnegan; Nuala Robson; P.M. Hocking; Aziza Suliman Ali; C.F. Inglehearn; Alan Stitt; Jim Curry

Proteomic profiling of the retinal dysplasia and degeneration chick retina

Sorcha Finnegan, Nuala Robson, P.M. Hocking, Aziza Suliman Ali, C.F. Inglehearn, Alan Stitt, Jim Curry

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: In our previous paper we undertook proteomic analysis of the normal developing chick retina to identify proteins that were differentially expressed during retinal development. In the present paper we use the same proteomic approach to analyze the development and onset of degeneration in the retinal dysplasia and degeneration (rdd) chick. The pathology displayed by the rdd chick resembles that observed in some of the more severe forms of human retinitis pigmentosa.

Original language	English
Pages (from-to)	7-17
Number of pages	11
Journal	Molecular Vision
Volume	16
Publication status	Published - 2010

ASJC Scopus subject areas

Ophthalmology

Cite this

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title = "Proteomic profiling of the retinal dysplasia and degeneration chick retina",

abstract = "Purpose: In our previous paper we undertook proteomic analysis of the normal developing chick retina to identify proteins that were differentially expressed during retinal development. In the present paper we use the same proteomic approach to analyze the development and onset of degeneration in the retinal dysplasia and degeneration (rdd) chick. The pathology displayed by the rdd chick resembles that observed in some of the more severe forms of human retinitis pigmentosa.",

author = "Sorcha Finnegan and Nuala Robson and P.M. Hocking and Ali, {Aziza Suliman} and C.F. Inglehearn and Alan Stitt and Jim Curry",

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AU - Finnegan, Sorcha

AU - Robson, Nuala

AU - Hocking, P.M.

AU - Ali, Aziza Suliman

AU - Inglehearn, C.F.

AU - Stitt, Alan

AU - Curry, Jim

PY - 2010

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N2 - Purpose: In our previous paper we undertook proteomic analysis of the normal developing chick retina to identify proteins that were differentially expressed during retinal development. In the present paper we use the same proteomic approach to analyze the development and onset of degeneration in the retinal dysplasia and degeneration (rdd) chick. The pathology displayed by the rdd chick resembles that observed in some of the more severe forms of human retinitis pigmentosa.

AB - Purpose: In our previous paper we undertook proteomic analysis of the normal developing chick retina to identify proteins that were differentially expressed during retinal development. In the present paper we use the same proteomic approach to analyze the development and onset of degeneration in the retinal dysplasia and degeneration (rdd) chick. The pathology displayed by the rdd chick resembles that observed in some of the more severe forms of human retinitis pigmentosa.

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M3 - Article

C2 - 20069063

VL - 16

SP - 7

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JO - Molecular Vision

JF - Molecular Vision

SN - 1090-0535

ER -

Proteomic profiling of the retinal dysplasia and degeneration chick retina

Abstract

ASJC Scopus subject areas

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