Psychosocial Interventions for Liver Transplant patients - Cochrane Protocol

Sharon Millen, Nuala Livingstone, Geraldine Macdonald

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Following work by the Organ Donor Taskforce there has been a 41% increase in the number of transplants carried out across the UK over the last 6 years with 4655 patients receiving an organ transplant last year. In 2014, the number of liver transplants in UK increased by 12% to 880 compared with 782 in 2013. With this number increasing annually, it is important to identify the most effective interventions to improve patient outcomes. Research indicates that although liver transplantation offers improved quality and length of life, the transplant experience extends far beyond hospital discharge. It is evident that liver recipients experience numerous stressors which can lead to maladaptive coping and significant psychological distress particularly in the early post-operative phase. These negative emotional states can lead to immune dysregulation and adverse health behaviours such as nonadherence to the transplant regimen. This can result in rehospitalisation and retransplantation due to rejection. Despite current evidence indicating that various psychosocial interventions are effective in improving health states for liver recipients, we do not know which of these strategies (or indeed which specific components of these) are most effective.
This review aims to assess the effectiveness of psychosocial interventions available for liver recipients. Participants= liver recipients (of any age). Interventions= psychosocial interventions currently in place for liver recipients of any duration, intensity, or frequency, and delivered in any setting in a variety of ways (e.g. web-based, by a facilitator, delivered individually/in groups, by phone). Comparisons= no intervention or treatment as usual. Primary Outcomes= 1) Health-Related Quality of Life; 2) psychological well-being (e.g. Post-Traumatic Stress Disorder, depression, anxiety, coping and optimism); 3) adherence (e.g. intake of medication, clinic attendance, alcohol, tobacco or illicit drug use).
Original languageEnglish
Publication statusPublished - 13 Sep 2015
Event17th Congress of the European Society for Organ Transplantation: FROM THE HEART F EUROPE T THE WORLD F TRANSPLANTATION - Meeting square , Brussels, Belgium
Duration: 13 Sep 201516 Sep 2015


Conference17th Congress of the European Society for Organ Transplantation
Abbreviated titleESOT Brussels 2015
Internet address


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