Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future?

G G Hanna, T Illidge

Research output: Contribution to journalArticle

5 Citations (Scopus)
169 Downloads (Pure)

Abstract

The goal of re-programming the host immune system to target malignancy with durable anti-tumour clinical responses has been speculated for decades. In the last decade such speculation has been transformed into reality with unprecedented and durable responses to immune checkpoint inhibitors seen in solid tumours. This mini-review considers the mechanism of action of immune modulating agents and the potential for combination with radiotherapy in the treatment of non-small cell lung cancer.

Original languageEnglish
Pages (from-to)726-731
Number of pages6
JournalClinical oncology (Royal College of Radiologists (Great Britain))
Volume28
Issue number11
Early online date09 Aug 2016
DOIs
Publication statusPublished - Nov 2016

Fingerprint

Non-Small Cell Lung Carcinoma
Immunotherapy
Radiotherapy
Neoplasms
Immune System
Therapeutics

Keywords

  • Immunotherapy
  • NSCLC
  • Radiotherapy
  • Combination

Cite this

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title = "Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future?",
abstract = "The goal of re-programming the host immune system to target malignancy with durable anti-tumour clinical responses has been speculated for decades. In the last decade such speculation has been transformed into reality with unprecedented and durable responses to immune checkpoint inhibitors seen in solid tumours. This mini-review considers the mechanism of action of immune modulating agents and the potential for combination with radiotherapy in the treatment of non-small cell lung cancer.",
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Radiotherapy and Immunotherapy Combinations in Non-small Cell Lung Cancer: A Promising Future? / Hanna, G G; Illidge, T.

In: Clinical oncology (Royal College of Radiologists (Great Britain)), Vol. 28, No. 11, 11.2016, p. 726-731.

Research output: Contribution to journalArticle

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KW - Combination

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