Rapid serological diagnosis of Helicobacter pylori: a need for caution and re-evaluation

A Heaney, J S Collins, R G Watson, R J McFarland, K B Bamford

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Screening for Helicobacter pylori in dyspeptic patients may improve selectivity for gastroscopy. Rapid serological tests based on ELISA technique are cheap, readily available and simple to use in the clinical setting. However local evaluation is essential in order to validate these techniques. Fifty-six dyspeptic patients (aged less than 45 yr) had a rapid serological test (Helisal) performed prior to gastroscopy. At gastroscopy H. pylori status was assessed using culture and histology. The Helisal sensitivity was 80 per cent, specificity 82 per cent. Screening patients with the Helisal test would have missed 6 patients with peptic ulcer disease and 2 with oesophagitis. The Helisal test did not perform satisfactorily as a screening test in selection of patients for gastroscopy.
Original languageEnglish
Pages (from-to)152-4
Number of pages3
JournalIrish journal of medical science
Volume167
Issue number3
Publication statusPublished - Jul 1998

ASJC Scopus subject areas

  • Medicine(all)

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