Re-irradiation for Locally Recurrent Lung Cancer: Evidence, Risks and Benefits

R. Rulach; G. G. Hanna; K. Franks; J. McAleese; S. Harrow

doi:10.1016/j.clon.2017.11.003

Re-irradiation for Locally Recurrent Lung Cancer: Evidence, Risks and Benefits

R. Rulach^*
, G. G. Hanna
, K. Franks
, J. McAleese
, S. Harrow

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

In spite of recent improvements in both the technical delivery of radiotherapy and systemic therapy in the treatment of non-small cell lung cancer, local recurrence rates after radiotherapy remain a significant challenge. In the setting of local relapse after radiotherapy, treatments such as surgical resection or radiofrequency ablation are often not appropriate owing to disease and patient factors. Re-irradiation may be a potential treatment option. This overview considers the published evidence and potential treatment strategies.

Original language	English
Pages (from-to)	101-109
Number of pages	9
Journal	Clinical Oncology
Volume	30
Issue number	2
Early online date	06 Dec 2017
DOIs	https://doi.org/10.1016/j.clon.2017.11.003
Publication status	Published - Feb 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Lung cancer
radiotherapy
re-irradiation
retreatment

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging

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Cite this

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abstract = "In spite of recent improvements in both the technical delivery of radiotherapy and systemic therapy in the treatment of non-small cell lung cancer, local recurrence rates after radiotherapy remain a significant challenge. In the setting of local relapse after radiotherapy, treatments such as surgical resection or radiofrequency ablation are often not appropriate owing to disease and patient factors. Re-irradiation may be a potential treatment option. This overview considers the published evidence and potential treatment strategies.",

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AU - Rulach, R.

AU - Hanna, G. G.

AU - Franks, K.

AU - McAleese, J.

AU - Harrow, S.

PY - 2018/2

Y1 - 2018/2

N2 - In spite of recent improvements in both the technical delivery of radiotherapy and systemic therapy in the treatment of non-small cell lung cancer, local recurrence rates after radiotherapy remain a significant challenge. In the setting of local relapse after radiotherapy, treatments such as surgical resection or radiofrequency ablation are often not appropriate owing to disease and patient factors. Re-irradiation may be a potential treatment option. This overview considers the published evidence and potential treatment strategies.

AB - In spite of recent improvements in both the technical delivery of radiotherapy and systemic therapy in the treatment of non-small cell lung cancer, local recurrence rates after radiotherapy remain a significant challenge. In the setting of local relapse after radiotherapy, treatments such as surgical resection or radiofrequency ablation are often not appropriate owing to disease and patient factors. Re-irradiation may be a potential treatment option. This overview considers the published evidence and potential treatment strategies.

KW - Lung cancer

KW - radiotherapy

KW - re-irradiation

KW - retreatment

UR - https://www.scopus.com/pages/publications/85039846003

U2 - 10.1016/j.clon.2017.11.003

DO - 10.1016/j.clon.2017.11.003

M3 - Article

AN - SCOPUS:85039846003

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JF - Clinical Oncology

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ER -

Re-irradiation for Locally Recurrent Lung Cancer: Evidence, Risks and Benefits

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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