Real time monitoring of the polymerisation of PMMA bone cement using Raman spectroscopy

Christopher P. Hagan, John F. Orr, Christina A. Mitchell, Nicholas J. Dunne

Research output: Contribution to journalArticle

11 Citations (Scopus)


In this investigation Raman spectroscopy was shown to be a method that could be used to monitor the polymerisation of PMMA bone cement. Presently there is no objective method that orthopaedic surgeons can use to quantify the curing process of cement during surgery. Raman spectroscopy is a non-invasive, non-destructive technique that could offer such an option. Two commercially available bone cements (Palacos® R and SmartSet® HV) and different storage conditions (4 and 22°C) were used to validate the technique. Raman spectroscopy was found to be repeatable across all conditions with the completion of the polymerisation process particularly easy to establish. All tests were benchmarked against current temperature monitoring methods outlined in ISO and ASTM standards. There was found to be close agreement with the standard methods and the Raman spectroscopy used in this study.
Original languageEnglish
Pages (from-to)2427-2433
Number of pages7
JournalJournal of Materials Science: Materials in Medicine
Issue number12
Publication statusPublished - Dec 2009

Fingerprint Dive into the research topics of 'Real time monitoring of the polymerisation of PMMA bone cement using Raman spectroscopy'. Together they form a unique fingerprint.

  • Cite this