The application of antibodies as therapeutic agents in the treatment of cancer now represents a significant proportion of the oncology drug arena. Despite this success, the ability to engineer and exploit antibodies in many different formats is ensuring that new avenues for their therapeutic application are constantly being examined. This review examines a selection of novel antibody-based therapeutic strategies that are currently in late preclinical and clinical evaluation.
Burden, R. E., Caswell, J., Fay, F., & Scott, C. J. (2012). Recent advances in the application of antibodies as therapeutics. FUTURE MEDICINAL CHEMISTRY, 4(1), 73-86. https://doi.org/10.4155/fmc.11.165