Recent advances in the application of antibodies as therapeutics.

Roberta E. Burden, Jill Caswell, Francois Fay, Christopher J. Scott

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

The application of antibodies as therapeutic agents in the treatment of cancer now represents a significant proportion of the oncology drug arena. Despite this success, the ability to engineer and exploit antibodies in many different formats is ensuring that new avenues for their therapeutic application are constantly being examined. This review examines a selection of novel antibody-based therapeutic strategies that are currently in late preclinical and clinical evaluation.
Original languageEnglish
Pages (from-to)73-86
Number of pages14
JournalFUTURE MEDICINAL CHEMISTRY
Volume4
Issue number1
Early online date15 Dec 2011
DOIs
Publication statusPublished - Jan 2012

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