Recent advances in the epidemiology, clinical and diagnostic features, and control of canine cardio-pulmonary angiostrongylosis

Hany M. Elsheikha*, Sarah A. Holmes, Ian Wright, Eric R. Morgan, David W. Lacher

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

63 Citations (Scopus)
70 Downloads (Pure)

Abstract

The aim of this review is to provide a comprehensive update on the biology, epidemiology, clinical features, diagnosis, treatment, and prevention of canine cardio-pulmonary angiostrongylosis. This cardiopulmonary disease is caused by infection by the metastrongyloid nematode Angiostrongylus vasorum. The parasite has an indirect life cycle that involves at least two different hosts, gastropod molluscs (intermediate host) and canids (definitive host). A. vasorum represents a common and serious problem for dogs in areas of endemicity, and because of the expansion of its geographical boundaries to many areas where it was absent or uncommon; its global burden is escalating. A. vasorum infection in dogs can result in serious disorders with potentially fatal consequences. Diagnosis in the live patient depends on faecal analysis, PCR or blood testing for parasite antigens or anti-parasite antibodies. Identification of parasites in fluids and tissues is rarely possible except post mortem, while diagnostic imaging and clinical examinations do not lead to a definitive diagnosis. Treatment normally requires the administration of anthelmintic drugs, and sometimes supportive therapy for complications resulting from infection.

Original languageEnglish
Article number92
Number of pages12
JournalVeterinary Research
Volume45
Issue number1
DOIs
Publication statusPublished - 27 Sept 2014
Externally publishedYes

ASJC Scopus subject areas

  • General Veterinary

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