Recent progress in the management of chronic cough

Woo-Jung Song, Jin An, Lorcan McGarvey

Research output: Contribution to journalReview articlepeer-review

Abstract

Chronic cough is a common clinical condition with significant impact on quality of life and for which effective therapy remains an unmet clinical need. Over the past decade, there has been a major shift in how we approach this problem, driven by better appreciation of the clinical manifestation of chronic cough and an improved understanding of the associated neurobiology. "Cough hypersensitivity syndrome" has been proposed as a new diagnostic term for chronic cough, encompassing different phenotypes of the condition. Accumulating evidence suggests that this new concept is clinically relevant. However, while it is gaining widespread endorsement within the allergy and respiratory community, raising its profile in routine clinical practice is a priority. Thus, the present paper reviews recent progress in our understanding and management of chronic cough, with focus on mechanistic and clinical studies. It also provides detail on knowledge gaps and future research directions.

Original languageEnglish
Pages (from-to)811-822
Number of pages12
JournalThe Korean journal of internal medicine
Volume35
Issue number4
Early online date20 May 2020
DOIs
Publication statusPublished - 01 Jul 2020

Keywords

  • Chronic Disease
  • Cough/diagnosis
  • Humans
  • Hypersensitivity
  • Quality of Life

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