Background A recombinant form of the alpha 2(IV)NC1 domain of type IV collagen has been shown to have potent anti-angiogenic activity although this peptide has not been studied in the context of proliferative retinopathies. In the current investigation we examined the potential for alpha 2(IV) NC1 to regulate retinal microvascular endothelial cell function using a range of in vitro and in vivo assay systems.
|Number of pages||7|
|Journal||Graefes Archive for Clinical and Experimental Ophthalmology|
|Publication status||Published - Apr 2007|
ASJC Scopus subject areas