Regulation of transendothelial transport in the cerebral microvessels: The role of second messengers-generating systems

F. Joo*, I. Lengyel, J. Kovacs, B. Penke

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Different elements of the intracellular signaling messenger systems have been detected in the course of our studies in the cerebral endothelial cells. It has been shown that the synthesizing enzymes of and substrate proteins for the second messenger molecules are present in the cerebral endothelial cells, and their activity and/or amount can change in pathological circumstances, i.e., during the formation of brain oedema. Pharmacological treatments interfering with the second messenger systems proved to be effective in the prevention of brain oedema formation.

Original languageEnglish
Pages (from-to)177-187
Number of pages11
JournalProgress in Brain Research
Volume91
Publication statusPublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Regulation of transendothelial transport in the cerebral microvessels: The role of second messengers-generating systems'. Together they form a unique fingerprint.

Cite this