TY - JOUR
T1 - Relative activity of triclabendazole metabolites against the liver fluke, Fasciola hepatica
AU - Halferty, Liam
AU - Brennan, Gerard
AU - Trudgett, Alan
AU - Hoey, Elizabeth
AU - Fairweather, Ian
PY - 2009/2/5
Y1 - 2009/2/5
N2 - A study has been carried Out to determine the relative activity Of triclabendazole (TCBZ) and its sulphoxide (TCBZ(center dot)SO) and sulphone (TCBZ(center dot)SO(2)) metabolites against the adult stage of the liver fluke, Fasciola hepatica. Flukes were incubated for 24 h in vitro in 15 mu g/ml of each of the compounds and prepared for scanning and transmission electron microscopy.
AB - A study has been carried Out to determine the relative activity Of triclabendazole (TCBZ) and its sulphoxide (TCBZ(center dot)SO) and sulphone (TCBZ(center dot)SO(2)) metabolites against the adult stage of the liver fluke, Fasciola hepatica. Flukes were incubated for 24 h in vitro in 15 mu g/ml of each of the compounds and prepared for scanning and transmission electron microscopy.
UR - http://www.scopus.com/inward/record.url?scp=58149464100&partnerID=8YFLogxK
U2 - 10.1016/j.vetpar.2008.10.007
DO - 10.1016/j.vetpar.2008.10.007
M3 - Article
C2 - 19027238
VL - 159
SP - 126
EP - 138
JO - Veterinary Parasitology
JF - Veterinary Parasitology
SN - 0304-4017
IS - 2
ER -