Relative Respiratory Syncytial Virus Cytopathogenesis in Upper and Lower Respiratory Tract Epithelium

Hong Guo Parke, Paul Canning, Isobel Douglas, Rémi Villenave, Liam G Heaney, Peter V Coyle, Jeremy D Lyons, Michael D Shields, Ultan F Power

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)
3 Downloads (Pure)

Abstract

Respiratory syncytial virus (RSV) is a major pathogen that primarily infects airway epithelium. Most infants suffer mild upper respiratory tract (URT) symptoms, while approximately one third progress to lower respiratory tract (LRT) involvement. Despite the ubiquity of URT infection, little is known about the relative cytopathogenesis of RSV infection in infant URT and LRT.
Original languageEnglish
Pages (from-to)842
Number of pages851
JournalAmerican Journal of Respiratory and Critical Care Medicine
Volume188
Issue number7
Early online date16 Aug 2013
DOIs
Publication statusPublished - 16 Aug 2013

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

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