Remote chiral induction in the organocatalytic hydrosilylation of aromatic ketones and ketimines

A.V. Malkov, A.J.P.S. Liddon, P. Ramirez-Lopez, L. Bendova, David Haigh, P. Kocovsky

Research output: Contribution to journalArticlepeer-review

132 Citations (Scopus)

Abstract

Lewis basic, metal-free pyridyloxazolines catalyze the redn. of prochiral arom. ketones and ketimines with Cl3SiH in good enantioselectivity (? 94% ee). Arene-arene interactions between the substrate and the catalyst are likely to play a role in the enantiodifferentiation process.
Original languageEnglish
Pages (from-to)1432-1435
Number of pages4
JournalAngewandte Chemie International Edition
Volume45
Issue number9
DOIs
Publication statusPublished - 20 Feb 2006

ASJC Scopus subject areas

  • Chemistry(all)

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