Sca-1+ progenitors derived from embryonic stem cells differentiate into endothelial cells capable of vascular repair after arterial injury

Qingzhong Xiao; Lingfang Zeng; Zhongyi Zhang; Andriana Margariti; Ziad A Ali; Keith M Channon; Qingbo Xu; Yanhua Hu

doi:10.1161/01.ATV.0000240251.50215.50

Sca-1+ progenitors derived from embryonic stem cells differentiate into endothelial cells capable of vascular repair after arterial injury

Qingzhong Xiao, Lingfang Zeng, Zhongyi Zhang, Andriana Margariti, Ziad A Ali, Keith M Channon, Qingbo Xu, Yanhua Hu

Research output: Contribution to journal › Article › peer-review

116 Citations (Scopus)

Abstract

Embryonic stem cells possess the ability to differentiate into endothelium. The ability to produce large volumes of endothelium from embryonic stem cells could provide a potential therapeutic modality for vascular injury. We describe an approach that selects endothelial cells using magnetic beads that may be used therapeutically to treat arterial injury.

Original language	English
Pages (from-to)	2244-51
Number of pages	8
Journal	Arteriosclerosis Thrombosis and Vascular Biology
Volume	26
Issue number	10
DOIs	https://doi.org/10.1161/01.ATV.0000240251.50215.50
Publication status	Published - 2006

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10.1161/01.ATV.0000240251.50215.50

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title = "Sca-1+ progenitors derived from embryonic stem cells differentiate into endothelial cells capable of vascular repair after arterial injury",

abstract = "Embryonic stem cells possess the ability to differentiate into endothelium. The ability to produce large volumes of endothelium from embryonic stem cells could provide a potential therapeutic modality for vascular injury. We describe an approach that selects endothelial cells using magnetic beads that may be used therapeutically to treat arterial injury.",

author = "Qingzhong Xiao and Lingfang Zeng and Zhongyi Zhang and Andriana Margariti and Ali, {Ziad A} and Channon, {Keith M} and Qingbo Xu and Yanhua Hu",

year = "2006",

doi = "10.1161/01.ATV.0000240251.50215.50",

language = "English",

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publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

T1 - Sca-1+ progenitors derived from embryonic stem cells differentiate into endothelial cells capable of vascular repair after arterial injury

AU - Xiao, Qingzhong

AU - Zeng, Lingfang

AU - Zhang, Zhongyi

AU - Margariti, Andriana

AU - Ali, Ziad A

AU - Channon, Keith M

AU - Xu, Qingbo

AU - Hu, Yanhua

PY - 2006

Y1 - 2006

N2 - Embryonic stem cells possess the ability to differentiate into endothelium. The ability to produce large volumes of endothelium from embryonic stem cells could provide a potential therapeutic modality for vascular injury. We describe an approach that selects endothelial cells using magnetic beads that may be used therapeutically to treat arterial injury.

AB - Embryonic stem cells possess the ability to differentiate into endothelium. The ability to produce large volumes of endothelium from embryonic stem cells could provide a potential therapeutic modality for vascular injury. We describe an approach that selects endothelial cells using magnetic beads that may be used therapeutically to treat arterial injury.

U2 - 10.1161/01.ATV.0000240251.50215.50

DO - 10.1161/01.ATV.0000240251.50215.50

M3 - Article

C2 - 16902164

SN - 1524-4636

VL - 26

SP - 2244

EP - 2251

JO - Arteriosclerosis Thrombosis and Vascular Biology

JF - Arteriosclerosis Thrombosis and Vascular Biology

IS - 10

ER -

Sca-1+ progenitors derived from embryonic stem cells differentiate into endothelial cells capable of vascular repair after arterial injury

Abstract

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