Secondary attack rate and family clustering of SARS-CoV-2 infection in children of healthcare workers with confirmed COVID-19

Shamez N Ladhani, Nick Andrews, Felicity Aiano, Frances Baawuah, Zahin Amin-Chowdhury, Kevin E Brown, Gayatri Amirthalingam, Mary E Ramsay, Thomas Waterfield, RAPID-19 Investigation team

Research output: Contribution to journalArticlepeer-review

Abstract

We measured serum SARS-CoV-2 antibodies in 215 children of healthcare workers to estimate secondary attack rates (SAR). Twenty-one families had a parent with confirmed COVID-19. There was strong evidence of family clustering (P<0.001): 20/21 (95.2%) children were seropositive in 9 families and none of 23 children in 12 other families.
Original languageEnglish
JournalClinical Infectious Diseases
Early online date17 Nov 2020
DOIs
Publication statusEarly online date - 17 Nov 2020

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