Secondary attack rate and family clustering of SARS-CoV-2 infection in children of healthcare workers with confirmed COVID-19

Shamez N  Ladhani; Nick  Andrews; Felicity  Aiano; Frances  Baawuah; Zahin  Amin-Chowdhury; Kevin E  Brown; Gayatri  Amirthalingam; Mary E  Ramsay; Thomas Waterfield; RAPID-19  Investigation team; Michael Corr; Lisa McFetridge; Hannah Mitchell

doi:10.1093/cid/ciaa1737

Secondary attack rate and family clustering of SARS-CoV-2 infection in children of healthcare workers with confirmed COVID-19

Shamez N Ladhani
, Nick Andrews
, Felicity Aiano
, Frances Baawuah
, Zahin Amin-Chowdhury
, Kevin E Brown
, Gayatri Amirthalingam
, Mary E Ramsay
, Thomas Waterfield
, RAPID-19 Investigation team
, Michael Corr
, Lisa McFetridge
, Hannah Mitchell

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

120 Downloads (Pure)

Abstract

We measured serum SARS-CoV-2 antibodies in 215 children of healthcare workers to estimate secondary attack rates (SAR). Twenty-one families had a parent with confirmed COVID-19. There was strong evidence of family clustering (P<0.001): 20/21 (95.2%) children were seropositive in 9 families and none of 23 children in 12 other families.

Original language	English
Journal	Clinical Infectious Diseases
Early online date	17 Nov 2020
DOIs	https://doi.org/10.1093/cid/ciaa1737
Publication status	Early online date - 17 Nov 2020

Access to Document

10.1093/cid/ciaa1737Licence: Unspecified

Secondary attack rate and family clustering of SARS-CoV-2 infection in children of healthcare workers with confirmed COVID-19
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. This work is made available online in accordance with the publisher’s policies. Please refer to any applicable terms of use of the publisher.
Accepted author manuscript, 617 KBLicence: Unspecified

Cite this

Ladhani, S. N., Andrews, N., Aiano, F., Baawuah, F., Amin-Chowdhury, Z., Brown, K. E., Amirthalingam, G., Ramsay, M. E., Waterfield, T., Investigation team, RAPID., Corr, M., McFetridge, L., & Mitchell, H. (2020). Secondary attack rate and family clustering of SARS-CoV-2 infection in children of healthcare workers with confirmed COVID-19. Clinical Infectious Diseases. Advance online publication. https://doi.org/10.1093/cid/ciaa1737

@article{e3bb2511a12a4688a012015deb655788,

title = "Secondary attack rate and family clustering of SARS-CoV-2 infection in children of healthcare workers with confirmed COVID-19",

abstract = "We measured serum SARS-CoV-2 antibodies in 215 children of healthcare workers to estimate secondary attack rates (SAR). Twenty-one families had a parent with confirmed COVID-19. There was strong evidence of family clustering (P<0.001): 20/21 (95.2\%) children were seropositive in 9 families and none of 23 children in 12 other families.",

author = "Ladhani, \{Shamez N\} and Nick Andrews and Felicity Aiano and Frances Baawuah and Zahin Amin-Chowdhury and Brown, \{Kevin E\} and Gayatri Amirthalingam and Ramsay, \{Mary E\} and Thomas Waterfield and \{Investigation team\}, RAPID-19 and Michael Corr and Lisa McFetridge and Hannah Mitchell",

year = "2020",

month = nov,

day = "17",

doi = "10.1093/cid/ciaa1737",

language = "English",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

publisher = "Oxford University Press",

}

Ladhani, SN, Andrews, N, Aiano, F, Baawuah, F, Amin-Chowdhury, Z, Brown, KE, Amirthalingam, G, Ramsay, ME, Waterfield, T, Investigation team, RAPID, Corr, M , McFetridge, L & Mitchell, H 2020, 'Secondary attack rate and family clustering of SARS-CoV-2 infection in children of healthcare workers with confirmed COVID-19', Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa1737

TY - JOUR

T1 - Secondary attack rate and family clustering of SARS-CoV-2 infection in children of healthcare workers with confirmed COVID-19

AU - Ladhani, Shamez N

AU - Andrews, Nick

AU - Aiano, Felicity

AU - Baawuah, Frances

AU - Amin-Chowdhury, Zahin

AU - Brown, Kevin E

AU - Amirthalingam, Gayatri

AU - Ramsay, Mary E

AU - Waterfield, Thomas

AU - Investigation team, RAPID-19

AU - Corr, Michael

AU - McFetridge, Lisa

AU - Mitchell, Hannah

PY - 2020/11/17

Y1 - 2020/11/17

N2 - We measured serum SARS-CoV-2 antibodies in 215 children of healthcare workers to estimate secondary attack rates (SAR). Twenty-one families had a parent with confirmed COVID-19. There was strong evidence of family clustering (P<0.001): 20/21 (95.2%) children were seropositive in 9 families and none of 23 children in 12 other families.

AB - We measured serum SARS-CoV-2 antibodies in 215 children of healthcare workers to estimate secondary attack rates (SAR). Twenty-one families had a parent with confirmed COVID-19. There was strong evidence of family clustering (P<0.001): 20/21 (95.2%) children were seropositive in 9 families and none of 23 children in 12 other families.

U2 - 10.1093/cid/ciaa1737

DO - 10.1093/cid/ciaa1737

M3 - Article

SN - 1058-4838

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

ER -

Secondary attack rate and family clustering of SARS-CoV-2 infection in children of healthcare workers with confirmed COVID-19

Abstract

Access to Document

Fingerprint

Cite this