@article{32b14c2dafd5431197fdb1507b2d7d0b,
title = "Seed dormancy in Arabidopsis thaliana is controlled by alternative polyadenylation of DOG1",
abstract = "DOG1 is a key regulator of seed dormancy in Arabidopsis and other plants. Interestingly, the C-terminus of DOG1 is either absent or not conserved in many plant species. Here, we show that in Arabidopsis DOG1 transcript is subject to alternative polyadenylation. In line with this, mutants in RNA 3' processing complex display weakened seed dormancy in parallel with defects in DOG1 proximal polyadenylation site selection, suggesting that the short DOG1 transcript, is functional. This is corroborated by the finding that the proximally polyadenylated short DOG1 mRNA is translated in vivo and complements the dog1 mutation. In summary, our findings indicate that the short DOG1 protein isoform produced from the proximally polyadenylated DOG1 mRNA is a key player in the establishment of seed dormancy in Arabidopsis and characterize a set of mutants in RNA 3' processing complex required for production of proximally polyadenylated functional DOG1 transcript.",
keywords = "alternatively polyadenylation , DOG1, Seed dormancy",
author = "Malgorzata Cyrek and Halina Fedak and Arkadiusz Ciesielski and Yanwu Guo and Aleksandra Sliwa and Lien Brzezniak and Katarzyna Krzyczmonik and Zbigniew Pietras and Szymon Kaczanowski and Fuquan Liu and Szymon Swiezewski",
year = "2016",
month = feb,
doi = "10.1104/pp.15.01483",
language = "English",
volume = "170",
pages = "947--955",
journal = "Plant Physiology",
issn = "0032-0889",
publisher = "American Society of Plant Biologists",
number = "2",
}