Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes

G. Collie, A.P. Reszka, Shozeb Haider, V. Gabelica, G.N. Parkinson, S. Neidle

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Quadruplex RNAs are less well understood than their DNA counterparts, yet of potentially high biological relevance. The interactions of several quadruplex-binding ligands with telomeric RNA quadruplexes are reported and compared with their binding to the analogous DNA quadruplexes.
Original languageEnglish
Pages (from-to)7482-7484
Number of pages3
JournalChemical Communications
Volume48
Issue number48
DOIs
Publication statusPublished - 2009

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Materials Chemistry
  • Metals and Alloys
  • Surfaces, Coatings and Films

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    Collie, G., Reszka, A. P., Haider, S., Gabelica, V., Parkinson, G. N., & Neidle, S. (2009). Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes. Chemical Communications, 48(48), 7482-7484. https://doi.org/10.1039/b901889a