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Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes

  • G. Collie
  • , A.P. Reszka
  • , Shozeb Haider
  • , V. Gabelica
  • , G.N. Parkinson
  • , S. Neidle

Research output: Contribution to journalArticlepeer-review

Abstract

Quadruplex RNAs are less well understood than their DNA counterparts, yet of potentially high biological relevance. The interactions of several quadruplex-binding ligands with telomeric RNA quadruplexes are reported and compared with their binding to the analogous DNA quadruplexes.
Original languageEnglish
Pages (from-to)7482-7484
Number of pages3
JournalChemical Communications
Volume48
Issue number48
DOIs
Publication statusPublished - 2009

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Materials Chemistry
  • Metals and Alloys
  • Surfaces, Coatings and Films

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