Homeobox gene expression was examined in the erythroleukaemic cell line TF-1. Expression of a number of HOX A, B and C genes, including HOX A7 was detected. Expression of this gene has not previously been reported in erythroleukaemic cell lines. A 2.1 kb full length cDNA of the HOX A7 gene was cloned. The predicted amino acid sequence C-terminal to the homeodomain consists of an alanine-rich region and a strongly negatively charged domain consisting entirely of aspartic and glutamic acid residues.
|Number of pages||5|
|Journal||Biochimica et biophysica acta|
|Publication status||Published - 08 Nov 1998|
ASJC Scopus subject areas
- Structural Biology
McIlhatton, M. A., Bremner, P., McMullin, M. F., Maxwell, A. P., Winter, P. C., & Lappin, T. R. (1998). Sequence characterisation and expression of homeobox HOX A7 in the multi-potential erythroleukaemic cell line TF-1. Biochimica et biophysica acta, 1442(2-3), 329-33.