Sequence characterisation and expression of homeobox HOX A7 in the multi-potential erythroleukaemic cell line TF-1

M A McIlhatton, P Bremner, M F McMullin, A P Maxwell, P C Winter, T R Lappin

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Homeobox gene expression was examined in the erythroleukaemic cell line TF-1. Expression of a number of HOX A, B and C genes, including HOX A7 was detected. Expression of this gene has not previously been reported in erythroleukaemic cell lines. A 2.1 kb full length cDNA of the HOX A7 gene was cloned. The predicted amino acid sequence C-terminal to the homeodomain consists of an alanine-rich region and a strongly negatively charged domain consisting entirely of aspartic and glutamic acid residues.
Original languageEnglish
Pages (from-to)329-33
Number of pages5
JournalBiochimica et biophysica acta
Volume1442
Issue number2-3
Publication statusPublished - 08 Nov 1998

ASJC Scopus subject areas

  • Biochemistry
  • Genetics
  • Structural Biology
  • Biophysics

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