Sequential expression of putative stem cell markers in gastric carcinogenesis

T Wang, C W Ong, J Shi, S Srivastava, B Yan, C L Cheng, W P Yong, S L Chan, K G Yeoh, B Iacopetta, M Salto-Tellez

Research output: Contribution to journalArticlepeer-review

86 Citations (Scopus)

Abstract

Gastric carcinogenesis has been well documented in the step-wise histopathological model, known as Correa pathway. Several biomarkers including CD44, Musashi-1 and CD133 have been reported as putative stem cell (PSC) markers.
Original languageEnglish
Pages (from-to)658-65
Number of pages8
JournalBritish Journal of Cancer
Volume105
Issue number5
DOIs
Publication statusPublished - 23 Aug 2011

Keywords

  • Precancerous Conditions
  • Humans
  • Aged
  • Antigens, CD44
  • Nerve Tissue Proteins
  • Gene Expression Regulation, Neoplastic
  • Aged, 80 and over
  • Antigens, CD
  • Stomach Neoplasms
  • Adult
  • Antineoplastic Combined Chemotherapy Protocols
  • Glycoproteins
  • Time Factors
  • Tumor Markers, Biological
  • Male
  • Clinical Trials, Phase II as Topic
  • Neoplastic Stem Cells
  • Predictive Value of Tests
  • Carcinoma
  • Biomarkers, Pharmacological
  • RNA-Binding Proteins
  • Middle Aged
  • Peptides
  • Immunohistochemistry
  • Female

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