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SERS of meso-droplets supported on superhydrophobic wires allows exquisitely sensitive detection of dipicolinic acid, an anthrax biomarker, considerably below the infective dose

  • Melody Cheung
  • , Wendy W. Y. Lee
  • , David P. Cowcher
  • , Royston Goodacre
  • , Steven E. J. Bell

Research output: Contribution to journalArticlepeer-review

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Abstract

Surface-enhanced Raman measurements of <1 μL analyte/colloid meso-droplets on superhydrophobic wires with hydrophilic tips allowed dipicolinic acid, a spore biomarker for Bacillus anthracis (anthrax), to be detected at 10(-6) mol dm(-3). This is equivalent to 18 spores, significantly below the infective dose of 10(4) spores and 2 orders of magnitude better than previous measurements.
Original languageEnglish
Pages (from-to)9925-9928
Number of pages4
JournalChemical Communications
Volume52
Issue number64
Early online date13 Jul 2016
DOIs
Publication statusPublished - 2016

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