Silk-inspired polymers and proteins

John G. Hardy*, Thomas R. Scheibel

*Corresponding author for this work

Research output: Contribution to journalLiterature review

70 Citations (Scopus)
594 Downloads (Pure)

Abstract

The biocompatibility and biodegradability of natural silk fibres and the benign conditions under which they (with impressive mechanical properties) are produced represent a biomimetic ideal. This ideal has inspired people in both academia and industry to prepare silk-mimetic polymers and proteins by chemical and/or biotechnological means. in the present paper, we aim to give an overview of the design principles of such silk-inspired polymers/proteins, their processing into various materials morphologies, their mechanical and biological properties, and, finally, their technical and biomedical applications.

Original languageEnglish
Pages (from-to)677-681
Number of pages5
JournalBiochemical society transactions
Volume37
Issue number4
DOIs
Publication statusPublished - 2009
EventMeeting on Bionanotechnology II - From Biomolecular Assembly to Applications - Cambridge, United Kingdom
Duration: 07 Jan 200909 Jan 2009

Keywords

  • biomimetic material
  • silk-inspired polymer
  • silkworm silk
  • spider silk
  • BOMBYX-MORI SILK
  • GENETICALLY-ENGINEERED SILK
  • SAMIA-CYNTHIA-RICINI
  • SPIDER-SILK
  • BETA-SHEETS
  • PERIODIC POLYPEPTIDES
  • STRUCTURAL-ANALYSIS
  • FIBROIN
  • COPOLYMERS
  • CRYSTALLIZATION

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