Simultaneous use of mitomycin-C with Baerveldt implantation

A. Azuara-Blanco, M.R. Moster, R.P. Wilson, C.M. Schmidt

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26 Citations (Scopus)

Abstract

BACKGROUND AND OBJECTIVE: To evaluate the outcome of Baerveldt implantation with adjunctive mitomycin-C in cases of complicated glaucoma. PATIENTS AND METHODS: The authors reviewed the charts of all patients who had undergone Baerveldt implantation with mitomycin-C between January 1993 and March 1995. Success was defined before data collection as an intraocular pressure (IOP) between 5 and 21 mm Hg, with or without medications. The success rate was calculated using the Kaplan-Meier actuarial method. RESULTS: Twenty-nine patients were identified. The mean preoperative IOP was 33.6 mm Hg, with an average of 2.0 antiglaucoma medications. The probability of success at 6 and 12 months for patients who received mitomycin-C during Baerveldt implantation was 82.4% and 73.3%, respectively. Choroidal effusion with a flat anterior chamber (10.3%), corneal edema (6.8%), and conjunctival erosion (6.8%) were the most frequent complications. CONCLUSION: In this retrospective series of complicated glaucoma, the implantation of a Baerveldt drainage device with adjunctive mitomycin-C had a satisfactory outcome. The complications encountered and the clinical efficacy were comparable to those of previously reported series in which mitomycin-C was not used.
Original languageEnglish
Pages (from-to)992-997
Number of pages6
JournalOphthalmic Surgery and Lasers
Volume28
Issue number12
Publication statusPublished - 01 Dec 1997

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    Azuara-Blanco, A., Moster, M. R., Wilson, R. P., & Schmidt, C. M. (1997). Simultaneous use of mitomycin-C with Baerveldt implantation. Ophthalmic Surgery and Lasers, 28(12), 992-997.