Solid-Phase Synthesis Of Oligonucleotides Containing 3'-Thiothymidine

R. Cosstick, Joseph Vyle

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

A 5'-O-monomethoxytritylthymidine-3'-S-thiophosphoramidite (3) has been used to prepare oligodeoxynucleotides containing 3'-thiothymidine on a solid phase support. The intermediate thiophosphites are most efficiently oxidised using tetrabutylammonium periodate.
Original languageEnglish
Pages (from-to)4693-4696
Number of pages4
JournalTetrahedron Letters
Volume30 (35)
DOIs
Publication statusPublished - 1989

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