Solubility study of tobramycin in room temperature ionic liquids: an experimental and computational based study

Richard Cunningham*, Nancy C. Forero-Martinez, Christopher Hardacre, Tristan G. A. Youngs, Marie E. Migaud

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Herein, we present a computational and experimental study assessing the solubility of tobramycin 1 in a series of hydrophilic room temperature ionic liquids (RTIL). We show that hydrophilic ionic liquids, in particular those containing acetate, [OAc], enable significantly enhanced solubilisation of tobramycin in comparison to conventional molecular solvents.

Original languageEnglish
Pages (from-to)107214-107218
Number of pages5
JournalRSC Advances
Volume6
Issue number109
Early online date04 Nov 2016
DOIs
Publication statusPublished - 2016

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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