Solutes determine the temperature windows for microbial survival and growth

Jason P. Chin, Julianne Megaw, Caroline L. Magill, Krzysztof Nowotarski, James P. Williams, Prashanth Bhaganna, Mark Linton, Margaret F. Patterson, Graham J.C. Underwood, Allen Y. Mswaka, John E. Hallsworth

Research output: Contribution to journalArticlepeer-review

99 Citations (Scopus)

Abstract

Microbial cells, and ultimately the Earth's biosphere, function within a narrow range of physicochemical conditions. For the majority of ecosystems, productivity is cold-limited, and it is microbes that represent the failure point. This study was carried out to determine if naturally occurring solutes can extend the temperature windows for activity of microorganisms. We found that substances known to disorder cellular macromolecules (chaotropes) did expand microbial growth windows, fungi preferentially accumulated chaotropic metabolites at low temperature, and chemical activities of solutes determined microbial survival at extremes of temperature as well as pressure. This information can enhance the precision of models used to predict if extraterrestrial and other hostile environments are able to support life; furthermore, chaotropes may be used to extend the growth windows for key microbes, such as saprotrophs, in cold ecosystems and manmade biomes.
Original languageEnglish
Pages (from-to)7835-7840
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume107
Issue number17
Early online date19 Apr 2010
DOIs
Publication statusPublished - 2010

ASJC Scopus subject areas

  • General

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