Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica

A.M. Flanagan; H.W.J. Edgar; F. Forster; A. Gordon; Ronnie Hanna; M. McCoy; Gerard Brennan; Ian Fairweather

doi:10.1016/j.vetpar.2010.10.037

Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica

A.M. Flanagan, H.W.J. Edgar, F. Forster, A. Gordon, Ronnie Hanna, M. McCoy, Gerard Brennan, Ian Fairweather

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

63 Citations (Scopus)

Abstract

A sheep trial was performed to standardise a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole (TCBZ) in Fasciola hepatica). The CRT employs the BIO K201 Fasciola coproantigen ELISA (Bio-X Diagnostics, Jemelle, Belgium) to test for the presence of F. hepatica coproantigens in a faecal sample. If it is coproantigen-positive, the CRT protocol recommends that faecal samples are re-tested for coproantigens at 14 days post-treatment (dpt), with negative testing at this point indicating TCBZ success.

Original language	English
Pages (from-to)	34-42
Number of pages	9
Journal	Veterinary Parasitology
Volume	176
Issue number	1
DOIs	https://doi.org/10.1016/j.vetpar.2010.10.037
Publication status	Published - 28 Feb 2011

ASJC Scopus subject areas

Parasitology
General Veterinary

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title = "Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica",

abstract = "A sheep trial was performed to standardise a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole (TCBZ) in Fasciola hepatica). The CRT employs the BIO K201 Fasciola coproantigen ELISA (Bio-X Diagnostics, Jemelle, Belgium) to test for the presence of F. hepatica coproantigens in a faecal sample. If it is coproantigen-positive, the CRT protocol recommends that faecal samples are re-tested for coproantigens at 14 days post-treatment (dpt), with negative testing at this point indicating TCBZ success.",

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AU - Forster, F.

AU - Gordon, A.

AU - Hanna, Ronnie

AU - McCoy, M.

AU - Brennan, Gerard

AU - Fairweather, Ian

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AB - A sheep trial was performed to standardise a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole (TCBZ) in Fasciola hepatica). The CRT employs the BIO K201 Fasciola coproantigen ELISA (Bio-X Diagnostics, Jemelle, Belgium) to test for the presence of F. hepatica coproantigens in a faecal sample. If it is coproantigen-positive, the CRT protocol recommends that faecal samples are re-tested for coproantigens at 14 days post-treatment (dpt), with negative testing at this point indicating TCBZ success.

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IS - 1

ER -

Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica

Abstract

ASJC Scopus subject areas

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