Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica

A.M. Flanagan; H.W.J. Edgar; F. Forster; A. Gordon; Ronnie Hanna; M. McCoy; Gerard Brennan; Ian Fairweather

doi:10.1016/j.vetpar.2010.10.037

Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica

A.M. Flanagan
, H.W.J. Edgar
, F. Forster
, A. Gordon
, Ronnie Hanna
, M. McCoy
, Gerard Brennan
, Ian Fairweather

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

A sheep trial was performed to standardise a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole (TCBZ) in Fasciola hepatica). The CRT employs the BIO K201 Fasciola coproantigen ELISA (Bio-X Diagnostics, Jemelle, Belgium) to test for the presence of F. hepatica coproantigens in a faecal sample. If it is coproantigen-positive, the CRT protocol recommends that faecal samples are re-tested for coproantigens at 14 days post-treatment (dpt), with negative testing at this point indicating TCBZ success.

Original language	English
Pages (from-to)	34-42
Number of pages	9
Journal	Veterinary Parasitology
Volume	176
Issue number	1
DOIs	https://doi.org/10.1016/j.vetpar.2010.10.037
Publication status	Published - 28 Feb 2011

ASJC Scopus subject areas

Parasitology
General Veterinary

Access to Document

10.1016/j.vetpar.2010.10.037

Cite this

@article{0b42736d31434af3bc31bd11d58336e2,

title = "Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica",

abstract = "A sheep trial was performed to standardise a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole (TCBZ) in Fasciola hepatica). The CRT employs the BIO K201 Fasciola coproantigen ELISA (Bio-X Diagnostics, Jemelle, Belgium) to test for the presence of F. hepatica coproantigens in a faecal sample. If it is coproantigen-positive, the CRT protocol recommends that faecal samples are re-tested for coproantigens at 14 days post-treatment (dpt), with negative testing at this point indicating TCBZ success.",

author = "A.M. Flanagan and H.W.J. Edgar and F. Forster and A. Gordon and Ronnie Hanna and M. McCoy and Gerard Brennan and Ian Fairweather",

year = "2011",

month = feb,

day = "28",

doi = "10.1016/j.vetpar.2010.10.037",

language = "English",

volume = "176",

pages = "34--42",

journal = "Veterinary Parasitology",

issn = "1873-2550",

publisher = "Elsevier B.V.",

number = "1",

}

TY - JOUR

T1 - Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica

AU - Flanagan, A.M.

AU - Edgar, H.W.J.

AU - Forster, F.

AU - Gordon, A.

AU - Hanna, Ronnie

AU - McCoy, M.

AU - Brennan, Gerard

AU - Fairweather, Ian

PY - 2011/2/28

Y1 - 2011/2/28

N2 - A sheep trial was performed to standardise a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole (TCBZ) in Fasciola hepatica). The CRT employs the BIO K201 Fasciola coproantigen ELISA (Bio-X Diagnostics, Jemelle, Belgium) to test for the presence of F. hepatica coproantigens in a faecal sample. If it is coproantigen-positive, the CRT protocol recommends that faecal samples are re-tested for coproantigens at 14 days post-treatment (dpt), with negative testing at this point indicating TCBZ success.

AB - A sheep trial was performed to standardise a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole (TCBZ) in Fasciola hepatica). The CRT employs the BIO K201 Fasciola coproantigen ELISA (Bio-X Diagnostics, Jemelle, Belgium) to test for the presence of F. hepatica coproantigens in a faecal sample. If it is coproantigen-positive, the CRT protocol recommends that faecal samples are re-tested for coproantigens at 14 days post-treatment (dpt), with negative testing at this point indicating TCBZ success.

U2 - 10.1016/j.vetpar.2010.10.037

DO - 10.1016/j.vetpar.2010.10.037

M3 - Article

SN - 1873-2550

VL - 176

SP - 34

EP - 42

JO - Veterinary Parasitology

JF - Veterinary Parasitology

IS - 1

ER -

Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this