Abstract
Acyclic amino alcohols can be obtained in high stereoisomeric purity by Stevens [2,3] rearrangement of tetrahydropyridine salts followed by reduction of the ketones and ring opening of the disubstituted pyrrolidine.
Original language | English |
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Pages (from-to) | 2827-2828 |
Number of pages | 2 |
Journal | Tetrahedron Letters |
Volume | 32 |
Issue number | 24 |
Publication status | Published - 10 Jun 1991 |
Keywords
- [2,3] SIGMATROPIC REARRANGEMENT
- AMINO KETONE
- AMINO ALCOHOL
- CHELATION CONTROLLED REDUCTION