STEREOSELECTIVE ROUTE TO HIGHLY FUNCTIONALIZED AMINO-ALCOHOLS

B COATES, JF MALONE, MT MCCARNEY, PJ STEVENSON, Paul Stevenson

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Acyclic amino alcohols can be obtained in high stereoisomeric purity by Stevens [2,3] rearrangement of tetrahydropyridine salts followed by reduction of the ketones and ring opening of the disubstituted pyrrolidine.

Original languageEnglish
Pages (from-to)2827-2828
Number of pages2
JournalTetrahedron Letters
Volume32
Issue number24
Publication statusPublished - 10 Jun 1991

Keywords

  • [2,3] SIGMATROPIC REARRANGEMENT
  • AMINO KETONE
  • AMINO ALCOHOL
  • CHELATION CONTROLLED REDUCTION

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