STOPP/START criteria for potentially inappropriate prescribing in older people: version 2

Denis O'Mahony, David O'Sullivan, Stephen Byrne, Marie Noelle O'Connor, Cristin Ryan, Paul Gallagher

Research output: Contribution to journalArticle

875 Citations (Scopus)
2121 Downloads (Pure)

Abstract

PURPOSE: screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required.

METHODS: we reviewed the 2008 STOPP/START criteria to add new evidence-based criteria and remove any obsolete criteria. A thorough literature review was performed to reassess the evidence base of the 2008 criteria and the proposed new criteria. Nineteen experts from 13 European countries reviewed a new draft of STOPP & START criteria including proposed new criteria. These experts were also asked to propose additional criteria they considered important to include in the revised STOPP & START criteria and to highlight any criteria from the 2008 list they considered less important or lacking an evidence base. The revised list of criteria was then validated using the Delphi consensus methodology.

RESULTS: the expert panel agreed a final list of 114 criteria after two Delphi validation rounds, i.e. 80 STOPP criteria and 34 START criteria. This represents an overall 31% increase in STOPP/START criteria compared with version 1. Several new STOPP categories were created in version 2, namely antiplatelet/anticoagulant drugs, drugs affecting, or affected by, renal function and drugs that increase anticholinergic burden; new START categories include urogenital system drugs, analgesics and vaccines.

CONCLUSION: STOPP/START version 2 criteria have been expanded and updated for the purpose of minimizing inappropriate prescribing in older people. These criteria are based on an up-to-date literature review and consensus validation among a European panel of experts.

Original languageEnglish
Pages (from-to)213-218
Number of pages6
JournalAge and Ageing
Volume44
Issue number2
Early online date16 Oct 2014
DOIs
Publication statusPublished - 2015

Fingerprint Dive into the research topics of 'STOPP/START criteria for potentially inappropriate prescribing in older people: version 2'. Together they form a unique fingerprint.

  • Cite this

    O'Mahony, D., O'Sullivan, D., Byrne, S., O'Connor, M. N., Ryan, C., & Gallagher, P. (2015). STOPP/START criteria for potentially inappropriate prescribing in older people: version 2. Age and Ageing, 44(2), 213-218. https://doi.org/10.1093/ageing/afu145