Strategies for living well with hormone-responsive advanced prostate cancer—a qualitative exploration

Lauren Matheson, Jo Nayoan, Carol Rivas, Jo Brett, Penny Wright, Hugh Butcher, Paul Jordan, Anna Gavin, Adam Glaser, Malcolm Mason, Richard Wagland, Eila Watson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Purpose: Due to recent treatment advances, men are increasingly living longer with advanced prostate cancer (PCa). This study sought to understand men’s experiences of living with and adjusting to advanced hormone-responsive PCa and how this influenced their quality of life (QoL), in order to highlight how support could be optimized. Methods: Participants were recruited through a UK wide survey—the ‘Life After Prostate Cancer Diagnosis’ study. In-depth telephone interviews were conducted with 24 men (aged 46–77 years) with advanced (stage IV) hormone-responsive PCa diagnosed 18–42 months previously. Thematic analysis was undertaken using a framework approach. Results: Most participants perceived their QoL to be relatively good, which was influenced by the following factors (enablers to ‘living well’ with PCa): a sense of connectedness to others, engagement in meaningful activities, resources (social, cognitive, financial), ability to manage uncertainty, utilization of adjustment strategies and support, communication and information from health professionals. Barriers to ‘living well’ with PCa were often the converse of these factors. These also included more troublesome PCa-related symptoms and stronger perceptions of loss and restriction. Conclusions: In our study, men living with advanced hormone-responsive PCa often reported a good QoL. Exploring the influences on QoL in men with advanced PCa indicates how future interventions might improve the QoL of men who are struggling. Further research is required to develop and test interventions that enhance QoL for these men.

Original languageEnglish
JournalSupportive Care in Cancer
Early online date06 Jul 2020
Publication statusEarly online date - 06 Jul 2020


  • Advanced
  • Health care
  • Metastatic prostate cancer
  • Patient experience
  • Qualitative
  • Quality of life

ASJC Scopus subject areas

  • Oncology


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