Strategies for multivessel revascularization in patients with diabetes

Michael E Farkouh; Michael Domanski; Lynn A Sleeper; Flora S Siami; George Dangas; Michael Mack; May Yang; David J Cohen; Yves Rosenberg; Scott D Solomon; Akshay S Desai; Bernard J Gersh; Elizabeth A Magnuson; Alexandra Lansky; Robin Boineau; Jesse Weinberger; Krishnan Ramanathan; J Eduardo Sousa; Jamie Rankin; Balram Bhargava; John Buse; Whady Hueb; Craig R Smith; Victoria Muratov; Sameer Bansilal; Spencer King; Michel Bertrand; Valentin Fuster; FREEDOM Trial Investigators; Timothy Lyons

doi:10.1056/NEJMoa1211585

Strategies for multivessel revascularization in patients with diabetes

Michael E Farkouh
, Michael Domanski
, Lynn A Sleeper
, Flora S Siami
, George Dangas
, Michael Mack
, May Yang
, David J Cohen
, Yves Rosenberg
, Scott D Solomon
, Akshay S Desai
, Bernard J Gersh
, Elizabeth A Magnuson
, Alexandra Lansky
, Robin Boineau
, Jesse Weinberger
, Krishnan Ramanathan
, J Eduardo Sousa
, Jamie Rankin
, Balram Bhargava

John Buse, Whady Hueb, Craig R Smith, Victoria Muratov, Sameer Bansilal, Spencer King, Michel Bertrand, Valentin Fuster, FREEDOM Trial Investigators, Timothy Lyons

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

1748 Citations (Scopus)

Abstract

In some randomized trials comparing revascularization strategies for patients with diabetes, coronary-artery bypass grafting (CABG) has had a better outcome than percutaneous coronary intervention (PCI). We sought to discover whether aggressive medical therapy and the use of drug-eluting stents could alter the revascularization approach for patients with diabetes and multivessel coronary artery disease.

Original language	English
Pages (from-to)	2375-84
Number of pages	10
Journal	New England Journal of Medicine
Volume	367
Issue number	25
DOIs	https://doi.org/10.1056/NEJMoa1211585
Publication status	Published - 20 Dec 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Aged
Angioplasty, Balloon, Coronary
Cardiovascular Diseases
Coronary Artery Bypass
Coronary Artery Disease
Diabetes Complications
Drug-Eluting Stents
Female
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Myocardial Infarction
Stroke

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10.1056/NEJMoa1211585

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Farkouh, M. E., Domanski, M., Sleeper, L. A., Siami, F. S., Dangas, G., Mack, M., Yang, M., Cohen, D. J., Rosenberg, Y., Solomon, S. D., Desai, A. S., Gersh, B. J., Magnuson, E. A., Lansky, A., Boineau, R., Weinberger, J., Ramanathan, K., Sousa, J. E., Rankin, J., ... Lyons, T. (2012). Strategies for multivessel revascularization in patients with diabetes. New England Journal of Medicine, 367(25), 2375-84. https://doi.org/10.1056/NEJMoa1211585

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title = "Strategies for multivessel revascularization in patients with diabetes",

abstract = "In some randomized trials comparing revascularization strategies for patients with diabetes, coronary-artery bypass grafting (CABG) has had a better outcome than percutaneous coronary intervention (PCI). We sought to discover whether aggressive medical therapy and the use of drug-eluting stents could alter the revascularization approach for patients with diabetes and multivessel coronary artery disease.",

keywords = "Aged, Angioplasty, Balloon, Coronary, Cardiovascular Diseases, Coronary Artery Bypass, Coronary Artery Disease, Diabetes Complications, Drug-Eluting Stents, Female, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Myocardial Infarction, Stroke",

author = "Farkouh, \{Michael E\} and Michael Domanski and Sleeper, \{Lynn A\} and Siami, \{Flora S\} and George Dangas and Michael Mack and May Yang and Cohen, \{David J\} and Yves Rosenberg and Solomon, \{Scott D\} and Desai, \{Akshay S\} and Gersh, \{Bernard J\} and Magnuson, \{Elizabeth A\} and Alexandra Lansky and Robin Boineau and Jesse Weinberger and Krishnan Ramanathan and Sousa, \{J Eduardo\} and Jamie Rankin and Balram Bhargava and John Buse and Whady Hueb and Smith, \{Craig R\} and Victoria Muratov and Sameer Bansilal and Spencer King and Michel Bertrand and Valentin Fuster and \{FREEDOM Trial Investigators\} and Timothy Lyons",

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doi = "10.1056/NEJMoa1211585",

language = "English",

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}

Farkouh, ME, Domanski, M, Sleeper, LA, Siami, FS, Dangas, G, Mack, M, Yang, M, Cohen, DJ, Rosenberg, Y, Solomon, SD, Desai, AS, Gersh, BJ, Magnuson, EA, Lansky, A, Boineau, R, Weinberger, J, Ramanathan, K, Sousa, JE, Rankin, J, Bhargava, B, Buse, J, Hueb, W, Smith, CR, Muratov, V, Bansilal, S, King, S, Bertrand, M, Fuster, V, FREEDOM Trial Investigators & Lyons, T 2012, 'Strategies for multivessel revascularization in patients with diabetes', New England Journal of Medicine, vol. 367, no. 25, pp. 2375-84. https://doi.org/10.1056/NEJMoa1211585

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T1 - Strategies for multivessel revascularization in patients with diabetes

AU - Farkouh, Michael E

AU - Domanski, Michael

AU - Sleeper, Lynn A

AU - Siami, Flora S

AU - Dangas, George

AU - Mack, Michael

AU - Yang, May

AU - Cohen, David J

AU - Rosenberg, Yves

AU - Solomon, Scott D

AU - Desai, Akshay S

AU - Gersh, Bernard J

AU - Magnuson, Elizabeth A

AU - Lansky, Alexandra

AU - Boineau, Robin

AU - Weinberger, Jesse

AU - Ramanathan, Krishnan

AU - Sousa, J Eduardo

AU - Rankin, Jamie

AU - Bhargava, Balram

AU - Buse, John

AU - Hueb, Whady

AU - Smith, Craig R

AU - Muratov, Victoria

AU - Bansilal, Sameer

AU - King, Spencer

AU - Bertrand, Michel

AU - Fuster, Valentin

AU - FREEDOM Trial Investigators

AU - Lyons, Timothy

PY - 2012/12/20

Y1 - 2012/12/20

N2 - In some randomized trials comparing revascularization strategies for patients with diabetes, coronary-artery bypass grafting (CABG) has had a better outcome than percutaneous coronary intervention (PCI). We sought to discover whether aggressive medical therapy and the use of drug-eluting stents could alter the revascularization approach for patients with diabetes and multivessel coronary artery disease.

AB - In some randomized trials comparing revascularization strategies for patients with diabetes, coronary-artery bypass grafting (CABG) has had a better outcome than percutaneous coronary intervention (PCI). We sought to discover whether aggressive medical therapy and the use of drug-eluting stents could alter the revascularization approach for patients with diabetes and multivessel coronary artery disease.

KW - Aged

KW - Angioplasty, Balloon, Coronary

KW - Cardiovascular Diseases

KW - Coronary Artery Bypass

KW - Coronary Artery Disease

KW - Diabetes Complications

KW - Drug-Eluting Stents

KW - Female

KW - Humans

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Myocardial Infarction

KW - Stroke

U2 - 10.1056/NEJMoa1211585

DO - 10.1056/NEJMoa1211585

M3 - Article

C2 - 23121323

SN - 0028-4793

VL - 367

SP - 2375

EP - 2384

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 25

ER -

Strategies for multivessel revascularization in patients with diabetes

Abstract

UN SDGs

Keywords

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