SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME

Rebecca Coll (Inventor), Luke A.J. O'Neill (Inventor), Matthew A Cooper (Inventor), Avril A B Robertson (Inventor), Kate Schroder (Inventor)

Research output: Patent

Abstract

The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.
Original languageEnglish
Patent numberPCT/AU2016/050103
Priority date16/02/2015
Filing date16/02/2016
Publication statusPublished - 25 Aug 2016

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Inflammasomes
Patents and inventions
Urea
Chemical activation

Cite this

Coll, R., O'Neill, L. A. J., Cooper, M. A., Robertson, A. A. B., & Schroder, K. (2016). SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME. (Patent No. PCT/AU2016/050103).
Coll, Rebecca (Inventor) ; O'Neill, Luke A.J. (Inventor) ; Cooper, Matthew A (Inventor) ; Robertson, Avril A B (Inventor) ; Schroder, Kate (Inventor). / SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME. Patent No.: PCT/AU2016/050103. Feb 16, 2016.
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Coll, R, O'Neill, LAJ, Cooper, MA, Robertson, AAB & Schroder, K Feb. 16 2016, SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME, Patent No. PCT/AU2016/050103.

SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME. / Coll, Rebecca (Inventor); O'Neill, Luke A.J. (Inventor); Cooper, Matthew A (Inventor); Robertson, Avril A B (Inventor); Schroder, Kate (Inventor).

Patent No.: PCT/AU2016/050103. Feb 16, 2016.

Research output: Patent

TY - PAT

T1 - SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME

AU - Coll, Rebecca

AU - O'Neill, Luke A.J.

AU - Cooper, Matthew A

AU - Robertson, Avril A B

AU - Schroder, Kate

PY - 2016/8/25

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N2 - The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.

AB - The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.

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Coll R, O'Neill LAJ, Cooper MA, Robertson AAB, Schroder K, inventors. SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME. PCT/AU2016/050103. 2016 Aug 25.