Abstract
We report the formation of highly scattering silver complexes of adenine, deoxyadenosine and 5'-dAMP under alkaline pH conditions in the colloidal silver solutions which are used for surface-enhanced Raman spectroscopy. These complexes, and other pH-dependent phenomena, help to explain the diversity of previously reported adenine SERS spectra. Using conditions which promote complex formation allows nucleotides to be detected at <1 ppm, even in solutions with high salt concentrations.
| Original language | English |
|---|---|
| Pages (from-to) | 3034-3037 |
| Number of pages | 4 |
| Journal | Analyst |
| Volume | 135 |
| Issue number | 12 |
| Early online date | 28 Sept 2010 |
| DOIs | |
| Publication status | Published - 2010 |
Keywords
- Adenine
- Adenosine Monophosphate
- Colloids
- Deoxyadenosines
- Hydrogen-Ion Concentration
- Molecular Structure
- Salts
- Silver
- Silver Compounds
- Spectrum Analysis, Raman
- Surface Properties