Surface Plasmon Resonance Biosensor Screening Method for Paralytic Shellfish Poisoning Toxins: A Pilot Interlaboratory Study

H.J. Van Den Top, Christopher Elliott, Simon Haughey, N. Viarino, H.P. Van Egmond, Luis Botana, Katrina Campbell

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)

Abstract

A surface plasmon resonance (SPR) optical biosensor method was developed for the detection of paralytic shellfish poisoning (PSP) toxins in shellfish. This application was transferred in the form of a prototype kit to seven laboratories using Biacore QSPR optical biosensor instrumentation for interlaboratory evaluation. Each laboratory received 20 shellfish samples across a range of species including blind duplicates for analysis. The samples consisted of 4 noncontaminated samples spiked in duplicate with a low level of PSP toxins (240 mu g STXcliHCl equivalents/kg), a high level of saxitoxin (825 mu g STXdiHCl/kg), 2 noncontarninated, and 14 naturally contaminated samples. All 7 participating laboratories completed the study, and HorRat values obtained were
Original languageEnglish
Pages (from-to)4206-4213
Number of pages8
JournalAnalytical Chemistry
Volume83
Issue number11
Early online date15 Apr 2011
DOIs
Publication statusPublished - 01 Jun 2011

ASJC Scopus subject areas

  • Analytical Chemistry

Fingerprint Dive into the research topics of 'Surface Plasmon Resonance Biosensor Screening Method for Paralytic Shellfish Poisoning Toxins: A Pilot Interlaboratory Study'. Together they form a unique fingerprint.

Cite this