Surgery for Good Prognosis Breast Cancers

Research output: Contribution to journalReview articlepeer-review


Purpose of Review:
The introduction of mammographic screening programmes has resulted increasing numbers of women with small breast cancers with biologically favourable characteristics. Many of these cancers may represent overdiagnosis, with a resulting treatment burden for women and healthcare costs for providers. Here, current surgical approaches to the treatment of such tumours are reviewed, together with alternative approaches to their management.

Recent Findings:
The surgical treatment of small, screen-detected breast cancers with biologically favourable characteristics has been extrapolated from the management of symptomatic breast cancers. There is no prospective randomised evidence for conventional open surgery compared with other approaches in this setting. A number of minimally invasive techniques, most notable vacuum-assisted excision, have been described for the management of these tumours, but at present, there is a lack of high-quality evidence to support their routine use. There are currently ongoing randomised trials evaluating risk-adapted surgical and minimally invasive approaches to the management of good prognosis disease.

It is possible that the surgical treatment of good prognosis screen-detected breast cancers may be de-escalated. However, high-quality evidence from ongoing prospective randomised trials will be required in order to change clinical practice.
Original languageEnglish
JournalCurrent Breast Cancer Reports
Early online date21 Apr 2021
Publication statusEarly online date - 21 Apr 2021


Dive into the research topics of 'Surgery for Good Prognosis Breast Cancers'. Together they form a unique fingerprint.

Cite this