Survival from acute myeloid leukaemia in patients over 55 years of age in Northern Ireland: A discrete population

M. F. McMullin*, G. MacKenzie

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Acute myeloid leukaemia is a disease of increasing frequency in the elderly. The aim of this study was to describe the survival and the factors influencing survival in a cohort older than 55 years in Northern Ireland, which has a relatively stable population. The median survival of the 92 cases identified in a 6-year period was 18 weeks with an actuarial survival overall at one year of 24%. Independent risk factors for survival were administration of chemotherapy with the intention to induce remission, social class 1 and 2, hepatomegaly, absence of splenomegaly, lower LDH, lower PB blast count, higher haemoglobin, female sex and WHO performance status 0-2. The results of this study suggest that survival from acute leukaemia in the elderly is very poor when an unselected patient cohort is considered.

Original languageEnglish
Pages (from-to)103-110
Number of pages8
JournalHematology
Volume6
Issue number2
DOIs
Publication statusPublished - 01 Jan 2001
Externally publishedYes

Keywords

  • Acute leukaemia
  • Elderly
  • Myeloid
  • Response

ASJC Scopus subject areas

  • Hematology

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