Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia

Jia Li; Matthew Wylie; Colin P McCoy

doi:10.5920/bjpharm.1126

Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia

Jia Li, Matthew Wylie, Colin P McCoy^*

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

47 Downloads (Pure)

Abstract

In this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanethiol to create asuperhydrophobic surface with static water contact angle more than 150°. The silver-coated PVC and superhydrophobic silver-coated PVC both exhibited excellent anti-adherent activity against MRSA and Pseudomonas aeruginosa.

Original language	English
Article number	1126
Number of pages	2
Journal	British Journal of Pharmacy
Volume	7
Issue number	2
DOIs	https://doi.org/10.5920/bjpharm.1126
Publication status	Published - 04 Nov 2022

Keywords

Energy Engineering and Power Technology
Management Science and Operations Research
Mechanical Engineering

Access to Document

10.5920/bjpharm.1126Licence: CC BY

Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia
Copyright 2022 The Authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 401 KBLicence: CC BY

Strategies to prevent ventilator-associated Pneumonia by modification of endotracheal tubes
Li, J. (Author), McCoy, C. (Supervisor) & Wylie, M. (Supervisor), Jul 2023
Student thesis: Doctoral Thesis › Doctor of Philosophy

Cite this

@article{1c5daf89dee348ef8f74cc2f8314ce1d,

title = "Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia",

abstract = "In this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanethiol to create asuperhydrophobic surface with static water contact angle more than 150°. The silver-coated PVC and superhydrophobic silver-coated PVC both exhibited excellent anti-adherent activity against MRSA and Pseudomonas aeruginosa.",

keywords = "Energy Engineering and Power Technology, Management Science and Operations Research, Mechanical Engineering",

author = "Jia Li and Matthew Wylie and McCoy, {Colin P}",

year = "2022",

month = nov,

day = "4",

doi = "10.5920/bjpharm.1126",

language = "English",

volume = "7",

journal = "British Journal of Pharmacy",

issn = "2058-8356",

publisher = "University of Huddersfield Press",

number = "2",

}

TY - JOUR

T1 - Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia

AU - Li, Jia

AU - Wylie, Matthew

AU - McCoy, Colin P

PY - 2022/11/4

Y1 - 2022/11/4

N2 - In this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanethiol to create asuperhydrophobic surface with static water contact angle more than 150°. The silver-coated PVC and superhydrophobic silver-coated PVC both exhibited excellent anti-adherent activity against MRSA and Pseudomonas aeruginosa.

AB - In this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanethiol to create asuperhydrophobic surface with static water contact angle more than 150°. The silver-coated PVC and superhydrophobic silver-coated PVC both exhibited excellent anti-adherent activity against MRSA and Pseudomonas aeruginosa.

KW - Energy Engineering and Power Technology

KW - Management Science and Operations Research

KW - Mechanical Engineering

U2 - 10.5920/bjpharm.1126

DO - 10.5920/bjpharm.1126

M3 - Article

SN - 2058-8356

VL - 7

JO - British Journal of Pharmacy

JF - British Journal of Pharmacy

IS - 2

M1 - 1126

ER -

Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia

Abstract

Keywords

Access to Document

Fingerprint

Student theses

Strategies to prevent ventilator-associated Pneumonia by modification of endotracheal tubes

Cite this