Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma.

E.L. Davenport, A. Zeisig, L.I. Aronson, H.E. Moore, S. Hockley, D. Gonzalez, E.M. Smith, M.V. Powers, S.Y. Sharp, P. Workman, G.J. Morgan, F.E. Davies

Research output: Contribution to journalArticle

63 Citations (Scopus)
Original languageEnglish
Pages (from-to)1804-1807
Number of pages4
JournalLeukemia
Volume24
Issue number10
DOIs
Publication statusPublished - Oct 2010

Keywords

  • Antineoplastic Combined Chemotherapy Protocols
  • Apoptosis
  • Benzhydryl Compounds
  • Benzoquinones
  • Blotting, Western
  • Cell Cycle
  • Cell Proliferation
  • Drug Synergism
  • HSP72 Heat-Shock Proteins
  • HSP90 Heat-Shock Proteins
  • Humans
  • Lactams, Macrocyclic
  • Multiple Myeloma
  • Pyrrolidinones
  • RNA, Messenger
  • RNA, Small Interfering
  • Reverse Transcriptase Polymerase Chain Reaction
  • Transcription Factor CHOP
  • Tumor Cells, Cultured

Cite this

Davenport, E. L., Zeisig, A., Aronson, L. I., Moore, H. E., Hockley, S., Gonzalez, D., Smith, E. M., Powers, M. V., Sharp, S. Y., Workman, P., Morgan, G. J., & Davies, F. E. (2010). Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma. Leukemia, 24(10), 1804-1807. https://doi.org/10.1038/leu.2010.168