Abstract
The tools and techniques developed for analytical cytology have become invaluable in expanding the development of cancer screening programs and biomarker discovery for personalized medicine. Detecting cellular, molecular, and functional changes of diseased tissue as defined by quantitative analytical methodologies has enhanced the field of medical diagnostics and prognostics. The focus of this review is to outline applications and recent technical advances in flow cytometry, laser scanning cytometry, image cytometry, and quantitative image analysis, as they pertain to clinical, research, and drug discovery applications.
| Original language | English |
|---|---|
| Pages (from-to) | 313-26 |
| Number of pages | 14 |
| Journal | Journal of Biophotonics |
| Volume | 5 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 2012 |
| Externally published | Yes |
Keywords
- Biomedical Research
- Cytological Techniques
- Drug Discovery
- Flow Cytometry
- laser scanning cytometry
- Lasers
- Molecular Imaging
- image cytometry
- computer-assisted image analysis
- cancer
- hematology
