Technologies supporting analytical cytology: clinical, research and drug discovery applications

Ivana K Cecic, Gerald Li, Calum MacAulay

Research output: Contribution to journalLiterature review

4 Citations (Scopus)

Abstract

The tools and techniques developed for analytical cytology have become invaluable in expanding the development of cancer screening programs and biomarker discovery for personalized medicine. Detecting cellular, molecular, and functional changes of diseased tissue as defined by quantitative analytical methodologies has enhanced the field of medical diagnostics and prognostics. The focus of this review is to outline applications and recent technical advances in flow cytometry, laser scanning cytometry, image cytometry, and quantitative image analysis, as they pertain to clinical, research, and drug discovery applications.

Original languageEnglish
Pages (from-to)313-26
Number of pages14
JournalJournal of Biophotonics
Volume5
Issue number4
DOIs
Publication statusPublished - Apr 2012
Externally publishedYes

Keywords

  • Biomedical Research
  • Cytological Techniques
  • Drug Discovery
  • Flow Cytometry
  • laser scanning cytometry
  • Lasers
  • Molecular Imaging
  • image cytometry
  • computer-assisted image analysis
  • cancer
  • hematology

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