Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.

G. Oliviero, J. Amato, N. Borbone, S. D'Errico, A. Galeone, L. Mayol, Shozeb Haider, O. Olubiyi, B. Hoorelbeke, J. Balzarini, G. Piccialli

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The biophysical and biological properties of unprecedented anti-HIV aptamers are presented. The most active aptamer (1L) shows a significant affinity to the HIV protein gp120.
Original languageEnglish
Pages (from-to)8971-8973
Number of pages3
JournalChemical Communications
Volume46(47)
Issue number47
DOIs
Publication statusPublished - 21 Dec 2010

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Human Immunodeficiency Virus Proteins
Oligonucleotides
DNA
Proteins

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Oliviero, G., Amato, J., Borbone, N., D'Errico, S., Galeone, A., Mayol, L., ... Piccialli, G. (2010). Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity. Chemical Communications, 46(47)(47), 8971-8973. https://doi.org/10.1039/c0cc02866e
Oliviero, G. ; Amato, J. ; Borbone, N. ; D'Errico, S. ; Galeone, A. ; Mayol, L. ; Haider, Shozeb ; Olubiyi, O. ; Hoorelbeke, B. ; Balzarini, J. ; Piccialli, G. / Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity. In: Chemical Communications. 2010 ; Vol. 46(47), No. 47. pp. 8971-8973.
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Oliviero, G, Amato, J, Borbone, N, D'Errico, S, Galeone, A, Mayol, L, Haider, S, Olubiyi, O, Hoorelbeke, B, Balzarini, J & Piccialli, G 2010, 'Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.', Chemical Communications, vol. 46(47), no. 47, pp. 8971-8973. https://doi.org/10.1039/c0cc02866e

Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity. / Oliviero, G.; Amato, J.; Borbone, N.; D'Errico, S.; Galeone, A.; Mayol, L.; Haider, Shozeb; Olubiyi, O.; Hoorelbeke, B.; Balzarini, J.; Piccialli, G.

In: Chemical Communications, Vol. 46(47), No. 47, 21.12.2010, p. 8971-8973.

Research output: Contribution to journalArticle

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AU - Balzarini, J.

AU - Piccialli, G.

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