Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.

G. Oliviero, J. Amato, N. Borbone, S. D'Errico, A. Galeone, L. Mayol, Shozeb Haider, O. Olubiyi, B. Hoorelbeke, J. Balzarini, G. Piccialli

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The biophysical and biological properties of unprecedented anti-HIV aptamers are presented. The most active aptamer (1L) shows a significant affinity to the HIV protein gp120.
Original languageEnglish
Pages (from-to)8971-8973
Number of pages3
JournalChemical Communications
Volume46(47)
Issue number47
DOIs
Publication statusPublished - 21 Dec 2010

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

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