Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.

G. Oliviero; J. Amato; N. Borbone; S. D'Errico; A. Galeone; L. Mayol; Shozeb Haider; O. Olubiyi; B. Hoorelbeke; J. Balzarini; G. Piccialli

doi:10.1039/c0cc02866e

Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.

G. Oliviero, J. Amato, N. Borbone, S. D'Errico, A. Galeone, L. Mayol, Shozeb Haider, O. Olubiyi, B. Hoorelbeke, J. Balzarini, G. Piccialli

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

The biophysical and biological properties of unprecedented anti-HIV aptamers are presented. The most active aptamer (1L) shows a significant affinity to the HIV protein gp120.

Original language	English
Pages (from-to)	8971-8973
Number of pages	3
Journal	Chemical Communications
Volume	46(47)
Issue number	47
DOIs	https://doi.org/10.1039/c0cc02866e
Publication status	Published - 21 Dec 2010

ASJC Scopus subject areas

Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Catalysis
General Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c0cc02866e

Cite this

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title = "Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.",

abstract = "The biophysical and biological properties of unprecedented anti-HIV aptamers are presented. The most active aptamer (1L) shows a significant affinity to the HIV protein gp120.",

author = "G. Oliviero and J. Amato and N. Borbone and S. D'Errico and A. Galeone and L. Mayol and Shozeb Haider and O. Olubiyi and B. Hoorelbeke and J. Balzarini and G. Piccialli",

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doi = "10.1039/c0cc02866e",

language = "English",

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T1 - Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.

AU - Oliviero, G.

AU - Amato, J.

AU - Borbone, N.

AU - D'Errico, S.

AU - Galeone, A.

AU - Mayol, L.

AU - Haider, Shozeb

AU - Olubiyi, O.

AU - Hoorelbeke, B.

AU - Balzarini, J.

AU - Piccialli, G.

PY - 2010/12/21

Y1 - 2010/12/21

N2 - The biophysical and biological properties of unprecedented anti-HIV aptamers are presented. The most active aptamer (1L) shows a significant affinity to the HIV protein gp120.

AB - The biophysical and biological properties of unprecedented anti-HIV aptamers are presented. The most active aptamer (1L) shows a significant affinity to the HIV protein gp120.

U2 - 10.1039/c0cc02866e

DO - 10.1039/c0cc02866e

M3 - Article

C2 - 20972507

SN - 1359-7345

VL - 46(47)

SP - 8971

EP - 8973

JO - Chemical Communications

JF - Chemical Communications

IS - 47

ER -

Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.

Abstract

ASJC Scopus subject areas

UN SDGs

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