TY - JOUR
T1 - TFOS Lifestyle: impact of elective medications and procedures on the ocular surface
AU - Gomes, José Alvaro P.
AU - Azar, Dimitri T.
AU - Baudouin, Christophe
AU - Bitton, Etty
AU - Chen, Wei
AU - Hafezi, Farhad
AU - Hamrah, Pedram
AU - Hogg, Ruth E.
AU - Horwath-Winter, Jutta
AU - Kontadakis, Georgios A.
AU - Mehta, Jodhbir S.
AU - Messmer, Elisabeth M.
AU - Perez, Victor L.
AU - Zadok, David
AU - Willcox, Mark D.P.
PY - 2023/7
Y1 - 2023/7
N2 - The word “elective” refers to medications and procedures undertaken by choice or with a lower grade of prioritization. Patients usually use elective medications or undergo elective procedures to treat pathologic conditions or for cosmetic enhancement, impacting their lifestyle positively and, thus, improving their quality of life. However, those interventions can affect the homeostasis of the tear film and ocular surface. Consequently, they generate signs and symptoms that could impair the patient's quality of life. This report describes the impact of elective topical and systemic medications and procedures on the ocular surface and the underlying mechanisms. Moreover, elective procedures performed for ocular diseases, cosmetic enhancement, and non-ophthalmic interventions, such as radiotherapy and bariatric surgery, are discussed. The report also evaluates significant anatomical and biological consequences of non-urgent interventions to the ocular surface, such as neuropathic and neurotrophic keratopathies. Besides that, it provides an overview of the prophylaxis and management of pathological conditions resulting from the studied interventions and suggests areas for future research. The report also contains a systematic review investigating the quality of life among people who have undergone small incision lenticule extraction (SMILE). Overall, SMILE refractive surgery seems to cause more vision disturbances than LASIK in the first month post-surgery, but less dry eye symptoms in long-term follow up.
AB - The word “elective” refers to medications and procedures undertaken by choice or with a lower grade of prioritization. Patients usually use elective medications or undergo elective procedures to treat pathologic conditions or for cosmetic enhancement, impacting their lifestyle positively and, thus, improving their quality of life. However, those interventions can affect the homeostasis of the tear film and ocular surface. Consequently, they generate signs and symptoms that could impair the patient's quality of life. This report describes the impact of elective topical and systemic medications and procedures on the ocular surface and the underlying mechanisms. Moreover, elective procedures performed for ocular diseases, cosmetic enhancement, and non-ophthalmic interventions, such as radiotherapy and bariatric surgery, are discussed. The report also evaluates significant anatomical and biological consequences of non-urgent interventions to the ocular surface, such as neuropathic and neurotrophic keratopathies. Besides that, it provides an overview of the prophylaxis and management of pathological conditions resulting from the studied interventions and suggests areas for future research. The report also contains a systematic review investigating the quality of life among people who have undergone small incision lenticule extraction (SMILE). Overall, SMILE refractive surgery seems to cause more vision disturbances than LASIK in the first month post-surgery, but less dry eye symptoms in long-term follow up.
U2 - 10.1016/j.jtos.2023.04.011
DO - 10.1016/j.jtos.2023.04.011
M3 - Article
C2 - 37087043
SN - 1937-5913
VL - 29
SP - 331
EP - 385
JO - The Ocular Surface
JF - The Ocular Surface
ER -