The antimicrobial effects of root canal irrigation and medication

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)


The role of microorganisms in the development and maintenance of pulpal and periapical inflammation have been well documented. The success of root canal treatment largely depends on the elimination of microbial contamination from the root canal system. Although mechanical instrumentation of root canals can reduce bacterial population, effective elimination of bacteria cannot be achieved without the use of antimicrobial root canal irrigation and medication. This review will discuss the antimicrobial effects of the known root canal irrigants and medicaments and explore future developments in the field.
Original languageEnglish
Pages (from-to)560-569
Number of pages10
JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics
Issue number4
Early online date16 Jan 2007
Publication statusPublished - 01 Apr 2007

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging
  • Surgery
  • Dentistry(all)


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